Chapter 27 Flashcards
CAD results in interruption of blood flow that can cause _______ or _______ as a results of __________________.
Ischemia
Infarction
Coronary Atherosclerosis
What is the most prevalent type of cardiovascular disease in adults?
CAD
The _______ attracts _____ and binds them to the site. The ___________ core of the LDLs is spilled into the underlayer of the _______ _________ envelop these fats and are now termed “foam cells.”
Inflammation
LDL
Triglyceride
Intima macrophages
This is the “_______ _______” seen in early stages of atherosclerosis. As the area enlarges, more ______, ________, ________, and smooth muscle fibers are drawn to the site and accumulate under the intima, _________ the vessel.
Fatty streak LDL Macrophages Platelets Narrowing
This causes ______ blood flow and ______ BP in the small coronary vessels.
Reduced
Higher
Diagnostic and clinical findings of CAD
SOB with activity
History of elevated blood lipids, smoking, poor dietary habits, secretary lifestyle and obesity.
Angina pectoris- chest pain due to myocardial ischemia
Women often have artificial signs and symptoms such as dyspnea, nausea, and weakness.
Major risk factors of coronary artery disease
Dyslipidemia, HTN, smoking, diabetes mellitus, obesity and sedentary lifestyle.
Nonmodifiable risk factors of CAD
- family history of CAD (first degree relative with cardiovascular disease at 55 years of age or younger for men and at 65 years of age or younger for women)
- increasing age (45 men; 55 woman)
- gender (more likely for woman)
- race (African Americans)
Modifiable risk factors of CAD
Hyperlipidemia Cigarette smoking, tobacco use Hypertension Diabetes Metabolic syndrome Obesity Physical inactivity
Myocardial Ischemia cause clinical signs and symptoms of chest pain _________ of a major coronary artery by more than ______ impairs blood flow enough to hamper ________ _________ when myocardial demand increases.
Narrowing
50%
Cellular metabolism
Myocardial ischemia develops if the ______ or oxygen content of coronary blood is insufficient to meet the _______ ________ of myocardial cells.
Flow
Metabolic demands
Causative events of angina pectoris include the 4 E’s:
- Eating a large meal
- Excitement
- Environment
- Exercise
And smoking
When _____ ______ diminishes to the heart muscle, the ___________ nervous system is activated, _______ the BP and heart rate. This ________ the oxygen and glucose needs of the cardiac cells.
Blood flow
Sympathetic
Raising
Increases
Cardiac ________ from lack of ________ occurs centrally, surrounded by varying levels of ________ tissue radiating outward from the site.
Necrosis
Perfusion
Ischemic
Necrotic cardiac tissue will ______ resume its prior ability to ______ but rather will form _____ ________.
Never
Contract
Scar tissue
Damage can occur to the ______ ______ of the heart, causing ______ arrhythmias.
Pacing system
Lethal
Assessment and diagnostic findings for myocardial infarction
- EKG changes (ST segment elevation)
- abnormalities in a 12-lead EKG
- elevation of cardiac enzymes
- elevated pulse and bp
- decreased O2 saturation
- CBC showing an elevation of WBC’s
- electrolyte abnormalities
Treatment/Medical intervention for CP/MI
M-morphine
O-oxygen
N-nitroglycerin (vasodilator)
A-aspirin