Chapter 26-Coagulation Modifier Drugs

Question 1

These drugs inhibit the action or formation of clotting factors and prevent clot formation

Answer 1

Anticoagulants

Question 2

These drugs inhibit platelet aggregation and prevent platelet plugs

Answer 2

Antiplatelet drugs

Question 3

These drugs alter platelet function

Answer 3

Hemorheologic drugs

Question 4

These drugs lyse (break down) existing clots

Answer 4

Thrombolytic drugs

Question 5

These drugs promote blood coagulation

Answer 5

Antifibrinolytics or hemostatic

Question 6

Drugs with this suffix are typically anticoagulant

Answer 6

-in, -an

Warfarin (Coumadin),
Enoxaparin (Levenox),
Heparin,
Dabigatran (Pradaxa),
Fondaparinux (Arixtra),
Argatroban (Argatroban)

Question 7

What are the indications for anticoagulant therapy?

Answer 7

Myocardial infarction, unstable angina, atrial fibrillation, mechanical heart valve, major orthopedic surgery

Question 8

What is the reversal drug for heparin?

Answer 8

Protamine sulfate

Question 9

What are the suffix used with thrombolytic drugs?

Answer 9

-ase

Anistreplase (Eminase),
Alteplase (Activase),
Reteplase (Retavase),
Tenecteplase (TNKase)

Question 10

What is the antidote for warfarin?

Answer 10

Vitamin K

Question 11

What herbal products have potential interactions with warfarin?

Answer 11

Capsicum pepper, Garlic, ginger, Gingo, St. John’s wort, feverfew

Question 12

What is the primary nursing diagnosis for coagulation modifier drugs?

Answer 12

Deficient knowledge related to the medication regimen and the need for alternate lifestyle

Question 13

What is the therapeutic PTT level?

Answer 13

1.5-2.5

Question 14

What is the therapeutic INR level?

Answer 14

2-3