Chapter 23-Antianginal Drugs Flashcards
Drugs with the suffix -trate are in which classification?
Nitrates/Nitrites
_____ _____ should be used with caution in patients with bronchial asthma as they can cause bronchoconstriction
Beta blockers
Beta Blockers are used to treat ____ angina
Exertional
What is the mechanism of action for nitrates and nitrites?
Vasodilation of coronary
Vasodilation of coronary arteries
What are the adverse effects of CCBs with regards to angina?
Rapid reduction of BP causes negative outcomes
What drugs interact negatively with calcium channel blockers?
Beta blockers (bradycardia & atrioventricular block),
Digoxin (increased digoxin levels),
Amiodarone (bradycardia and decreased cardiac output),
Statins (increased risk of statin toxicity),
Cyclosporine (possible toxicity of either drug)
What are the calcium channel blockers available for IV administration?
Nicardapine (Cardene),
Verapamil (Calan, Isoptin, Verelan),
Diltiazem (Cardizem, Dilacor, Tiazac)
What suffix is common for CCBs ?
- pine,
- zem,
- mil
What is the mechanism of action for antianginal medication?
Increases delivery of oxygen rich blood to cardiac tissues,
Reduces oxygen consumption by the coronary vessels
What should a patient’s pulse rate be prior to administering antianginal medication?
Between 61 (minimum) and 99 (maximum)
If a patient has weight gain of _____ pounds or more in 24 hours or _____ pounds or more in one week likely indicates edema.
2,
5
Patients taking calcium channel blocker’s should not consume _____
Grapefruit
How is nitroglycerin stored?
Amber colored glass container with metal lid to avoid exposure to heat, light, moisture, and cotton filler
When a patient does not respond to nitroglycerin it may be an indication of a _____ _____
Myocardial infarction
When nitroglycerin is place under the tongue the patient should feel _____ or ______. This is an indicator of correct potency.
Burning or stinging
