Chapter 25-Antidysrhthmic Drugs Flashcards
What is the mechanism of action for antidysrhythmic drugs?
They correct abnormal cardiac electrophysiologic function
What do class 1a antidysrhthmic drugs treat?
Atrial fibrillation,
premature atrial contraction,
premature ventricular contraction
What are the class 1A drugs?
Disopyramide,
Procainamide,
Quinidine
What do Class 1B antidysrhthmic drugs treat?
Ventricular dysrhythmias,
Atrial & Ventricular tackydysrhythmias
What are the Class 1B drugs?
Lidocaine-ventricular dysrhythmias only,
Phenytoin-atrial and ventricular tackydysrhythmias caused by digitalis toxicity or long QT syndrome
What are the Class 1C drugs?
Flecainide,
Propafenone
What do Class 1C antidysrhthmic drugs treat?
Ventricular tachycardia and supraventricular tachycardia dysrhythmias, atrial fibrillation and flutter
What do Class II antidysrhthmic drugs treat?
Supraventricular and ventricular dysrhythmias
What are the Class II drugs?
Beta Blockers…
Atenolol,
Esmolol,
Metoprolol
What are the Class III drugs?
Amiodarone, Dronedarone, Dofetilide, Ibutilide, Sotalol
What do Class III antidysrhthmic drugs treat?
Life-threatening ventricular tachycardia or fibrillation, atrial fibrillation or flutter resistant to other drug therapy
What do Class IV antidysrhthmic drugs treat?
Paroxysmal supraventricular tachycardia
What are the Class IV drugs?
Calcium channel blockers…
Diltiazem ,
Verapamil
Which antidysrhythmic drug has the potential to cause systemic lupus?
Procainamide
Which antidysrhythmic drug can cause tinnitus and/or hearing loss?
Quinidine