chapter 25 Flashcards
percentage of fluid by weight
65%
people with ________ are more likely to experience fluid imbalance
lower or higher percentage
lower
fluid percentage depends on
age
radio of adipose connective tissue to skeletal muscle tissue
skeletal muscle tissue has ____ water than adipose connective tissue
more or less
more
2/3 of fluid is
intracellular fluid
1/3 of fluid is
extracellular fluid
2/3 of ECF is in
interstitial fluid
1/3 of ECF is in
blood plasma
ICF has higher concentration of these cations
K and Mg
ECF has higher concentration of these cations
Na
higher concentration of proteins are in
ICF
anions in ICF
PO
anions in ECF
Cl chloride
HCO bicarbonate
water moves by osmosis from ______ to _____
hypotonic solution
hypertonic solution
de menos a mas
what happen during fluid intake
blood plasma is hypotonic
cells are hypertonic
what happen during dehydration
blood plasma is hypertonic
cells are hypotonic
2 categories of fluid intake
ingested or preformed water 2300ml/day
metabolic water 200ml/day
ways of fluid output
expired air
sweat
cutaneous transpiration
feces
urine
sensible water loss
measurable
feces and urine
60% of fluid is lost through
urine
insensible water loss
unmeasurable
expired air, sweat and transpiration
obligatory water loss
always happens
expired air, sweat and transpiration
feces and 500ml urine
facultative water loss
controlled water loss by hormones or level of hydration
most urine
causes of fluid imbalance
change in osmolarity
excess or deficiency of body fluid
fluid imbalance with constant osmolarity
isotonic fluid is lost or gained
volume depletion
volume excess
volume depletion
isotonic fluid loss is greater
severe burns, chronic vomiting, diarrhea, hemorrhaging, hyposecretion of aldosterone
volume excess
decreased isotonic fluid loss through the kidneys
aldosterone hypersecretion
fluid imbalance with changes in osmolarity
no-isotonic fluid gain or loss
dehydration
hypotonic hydration
dehydration
water loss is greater than solute loss
hypotonic hydration
water intoxication or positive water balance
ADH hypersecretion
drinking too much water
fluid sequestration
fluid is distributed abnormally
edema
what happen when fluid intake is less than fluid output
blood pressure and blood volume decrease
maybe osmolarity increases
what happen when fluid intake is greater than fluid output
blood pressure and blood volume increase
maybe osmolarity decreases
stimuli that activates thirst center
decreased blood volume and blood pressure (angiotensin II)
increased blood osmolarity (ADH)
decreased salivary secretions
stimuli that inhibits thirst center
increased blood volume and blood pressure
decreased blood osmolarity
increased salivary secretions
distension of the stomach (stretch)
hormones that decrease water loss
ADH
angiotensin II
aldosterone
hormone that increases water loss
atrial natriuretic peptide ANP
nonelectrolyte
don’t dissociate in solution
electrolyte
dissociate
osmotic pressure depends on
the number of solutes
sodium functions
depolarization of skeletal muscle, neurons and cardiac muscle
excitatory postsynaptic potentials
cotransport
blood sodium is regulated by these hormones
aldosterone: retains Na and water, maintains its concentration
ADH: retains water, decreases Na concentration
ANP: increases Na and H2O excretion, decreases Na concentration
Na concentration decreases, ECF becomes
hypotonic or hypertonic
hypotonic
Na concentration increases, ECF becomes
hypotonic or hypertonic
hypertonic
Na above normal level
hypernatremia
Na below normal level
hyponatremia
potassium functions
repolarization in skeletal muscle and cardiac muscle
controls heart rhythm
establishing inhibitory postsynaptic potentials
K is regulated by this hormone
aldosterone: K secretion by kidneys, decreases K concentration
most of K is lost in
urine
K cannot be stored
true
what happens during hyperkalemia (K)
too much K in blood plasma
K moves from ECF to ICF
what happens during hypokalemia (K0
less K in blood plasma
K moves from ICF to ECF
what happens during acidosis (K)
too much H in ECF, pH decreases
H moves from ECF to ICF
K moves from ICF to ECF
what happens during alkalosis (K)
less H in ECF, pH increases
H moves from ICF to ECF
K moves from ECF to ICF
acidosis results in
hyperkalemia or hypokalemia
hyperkalemia
alkalosis results in
hyperkalemia or hypokalemia
hypokalemia
insulin ______ blood plasma K
decreases or increases
decreases
K moves from ECF into ICF
angiotensin II is a
vasoconstrictor or vasodilator
vasoconstrictor
______ is released from the kidneys and converts angiotensinogen into angiotensin I
renin
function of renin and angiotensin-converting enzyme ACE
convert angiotensin I into angiotensin II
function of renin and angiotensin-converting enzyme ACE
convert angiotensin I into angiotensin II
effects of angiotensin II
vasoconstriction, increases blood pressure
decreases urine output from kidneys
stimulates the thirst center
stimulates hypothalamus (ADH) and adrenal cortex (aldosterone)
antidiuretic hormone is also called
vasopressin
AHD is synthesized by _________ but stored in the ______
hypothalamus
posterior pituitary
angiotensin is synthesized by
liver
ADH stimuli
low blood pressure
low blood volume
increased blood osmolarity
angiotensin II
ADH effects
stimulates the thirst center
increases water retention (aquaporins), decreases osmolarity
vasoconstriction (high doses)
aldosterone stimuli
angiotensin II
increased blood plasma K
aldosterone effects
reabsorption of Na and water
increased retention and loss of K
ANP stimuli
increased stretch
increased blood pressure and volume
ANP effects
vasodilation
inhibits Na and water reabsorption (+ fluid loss)
increases glomerular filtration rate
inhibits renin release
normal arterial blood pH
7.35-7.45
volatile acids involve
co2 and carbonic acid
fixed acids doesn’t involve _______ but involve
co2
H and bicarbonate
volatile acids are regulated by
respiration
CO2 expired
fixed acids are regulated by
kidneys
absorption and elimination of H and HCO
definition of fixed acids
water from metabolic processes
examples of fixed acids
lactic acid
phosphoric acid
ketoacids
regulatory processes of the kidneys and respiratory system are called
physiologic buffering systems
type A intercalated cells
fight Acids
respond to increased H
what do type A cells do (kidneys)
eliminate H (acid)
synthesize HCO (base) which is absorbed
type A intercalated cells
fight Bases
respond to decreased H
what do type A cells do (kidneys)
absorb H (acids)
synthesize HCO (base) which is excreted in urine
chemical buffers are _______ than physiologic buffers
slower or faster
faster
3 most important chemical buffering systems
protein (cells and blood)
phosphate (PO43-) (cells)
bicarbonate (HCO3-) (ECF)