Chapter 24 Flashcards
Phenotypes fall on a range without clear division: quantitative, continuous. Why are they called continuous?
- exhibit a spectrum of possible values
- trait can vary smoothly across a continuum than falling into distinct categories
Why is the relationship of phenotype to genotype complex?
What type of inheritance does this contribute to?
- due to multiple genes/loci
- polygenic inheritance
What is the unabbreviated version of QTL?
quantitative trait loci
What strongly influences multifactorial characteristics?
- loci
- environment
What does meristic mean?
- whole numbers
- traits that are countable and can’t be continuous
Define threshold characteristics?
- two phenotypes
- underlying quantitative inheritance (disease susceptibility)
What does it mean when alleles are additive at all loci?
- for every gene involved in a trait, each allele contributes a predictable amount to the overall phenotype
- no interaction between alleles at different loci
Give an example of “additive, but not equal”
A+A+B-B- = A-A-B+B+
A+A+ does not = B+B+
Can environmental influences make characteristics more continuous?
yes
What does a normal distribution curve look like?
- a simple hill
- “bell-shaped”
What does a skewed distribution curve look like?
large hill, then decrease in hill height
What does a bimodal distribution curve look like?
- two hills
- one large, one medium
For normal distribution, what is the “mean”?
What’s its unit?
- average
- (line over) X
What is standard deviation (s)?
- calculated from the variance
- measuremnet of how far the typical individual is from the mean
What does it mean when the value are high for standard deviation?
Low?
high:
- wide curve
low:
- narrow curve
How do you calculate variance form standard deviation (s)?
variance = (standard deviation)^2
= s^2
What does correlation measure?
how strongly the values of two different quantitative characteristics relate to each other
What does it mean when the correlation value is 1?
0?
-1?
1:
- perfect correspondence (one is perfectly proportional to the other)
0:
- no correspondence (no relation between the two characteristics)
-1:
- perfect correspondence (inversely proportional)
What does it mean when the correlation between parental values and offspring is high?
- higher genetic contribution to the characteristics
- lower environmental contribution
What does regression measure?
What is it used for?
- how two characteristics relate to each other
- predict the actual value of one characteristic, given the value of the other
What is regression coefficient?
the slope of the regression line
What is the formula that corresponds to population variance?
Vp = Vg + Ve + Vge
Within the population phenotypic variance function Vp = Vg + Ve + Vge, what is Vg?
Ve?
Vge?
Vg:
- genetic variance
- all different contributions to phenotype
Ve:
- environmental variance
- contribution of environmental factors to phenotypic variance
Vge:
- genetic-environmental interaction variance
- contributes to phenotypic variance
- environment factors may have different effects on genotypes
What are the components of genetic variance (Vg)?
Vg = Va + Vd + Vi