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Nursing > Chapter 23 drugs for neurological disorders > Flashcards

Chapter 23 drugs for neurological disorders Flashcards

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0
Q

Examples of ACE inhibitors

A

Tacrine
Cognex
Aricept
Exelon

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1
Q

The drug prescribed to treat Parkinsonism by replacing the neurotransmitter
Carbidopa or levodopa

A

Levodopa

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2
Q

Which drug prolongs action of levodopa and can decrease on-off fluctuations in patients with Parkinsonism

A

Selegiline

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3
Q

Initial dose of carbidopa and levodopa

A

10/100 mg tid/qid

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4
Q

Maintenance dose of carbidopa levodopa

A

25/250 tid/qid

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5
Q 
Possible side effect of carbidopa levodopa 
Diarrhea
Anxiety
Nasal stuffiness 
Dizziness
A

Dizziness

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6
Q

Foods that should be avoided when taking selegiline (Eldepryl)

A

Aged cheeses
Chocolate
Yogurt
These food are high in Tyramine which may cause hypertensive crisis

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7
Q

What decreases the effect of rivastigmine
Atypical antidepressants
SSRI
Tricyclics

A

TRICYCLICS

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8
Q

Selected drugs to treat Parkinson’s or pseudo

A

Cogentin
Artane
Akineton
Benadryl

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9
Q

Side effects of antiparkinsonism-anticholinergics

A 
Red as a beet
Dry as a bone
Mad as a hatter
Hot as a hare 
Can't see
Can't pee 
Can't spit
Can't shit
Nausea and vomiting
Postural hypotension
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10
Q

Contraindications of antiparkinsonism-anticholinergics

A

Glaucoma
GU obstruction
BPH

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11
Q

Side effects of levodopa

A

Gi upset
Dyskinesia
Dystonic movements orthostasis hypotension
Cardiac dysrhythmias
Psychosis
Agranulocytosis - most serious side effect

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12
Q

What is benefit of drug combination of carbidopa and levodopa (Sinemet)

A

Allows more dopamine to reach the brain
Allows once a day dosing
Smaller doses of levodopa are required to achieve desired effect

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13
Q

Name some dopamine agonists (stimulate dopamine receptors)

A 
Symmetrel 
Parlodel 
Mirapex 
Requip 
Neupro
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14
Q

Name MAO-B inhibitors

A

Selegiline

Rasagline

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15
Q

Name COMT inhibitors

A

Tolcarpone - monitor LFTs

Entacopone

16
Q

With Parkinson’s drugs what vitamin do you need to limit

A

Vitamin B6 to normal doses

Dried beans, certain cereals

17
Q

Name characteristics of myasthenia gravis

A

Muscular weakness and fatigue
Resp muscle paralysis
Ptosis
Difficulty chewing and swallowing

18
Q

Pathophysiology of MG

A

Lack of acetylcholine reaching cholinergic receptors

19
Q

What meds is MG treated with

A

AChe inhibitor

20
Q

Normal dose of namenda

A

10 mg morning and night

Nursing (10 decks)

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