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Nursing > Antiinflammatory Drugs chapter 25, 26' 35' 36 and 39 > Flashcards

Antiinflammatory Drugs chapter 25, 26' 35' 36 and 39 Flashcards

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0
Q

Well absorbed from GI tract
Metabolized in liver, excreted by kidneys
Toxic to the liver
Inhibits prostaglandin synthesis (weak)
Inhibits hypothalamic heat regulating center
Well tolerated
Use with caution in patients with anemia

A

Tylenol

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1
Q

Contraindications of Tylenol

A

Liver dx
Viral hepatitis
Alcoholism
Renal impairment

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2
Q

Tylenol overdose

A

No more than 4000 mg day

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3
Q

Anti inflammatory drugs pathophysiology

A

Inflammation - response to injury and infection

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4
Q

Cardinal signs of inflammation

A 
Redness
Swelling 
Heat
Pain
Loss of function
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5
Q

Chemical mediator of interest in anti inflammatory drugs

A

Prostaglandin

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6
Q

Antiinflammstory drug groups

A

NSAIDs

Corticosteroids

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7
Q

Aspirin action

A

Antiinflsmmstory, anti platelet, antipyretic effect

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8
Q

Aspirin pharmakinetics

A

Well absorbed from GI tract

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9
Q

Aspirin caution

A

Do not take with other NSAIDs (decreases effectiveness of other NSAID)
Avoid during third trimester
Do not give to children

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10
Q

Common side effect of aspirin

A

Gastric distress

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11
Q

Patient care plan

A

Assess for allergy/sensitivity, pain, inflammation and fever
Nursing diagnosis - alteration in comfort
Plan - administer med as directed with food

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12
Q

Para-chlorobenzoic acid

A 
Indocin
Tolectin
Highly protein bound
Very irritating
May cause sodium and water retention and raise BP
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13
Q

Phenylactic-acid derivatives

A

Voltaren
No antipyretic effects
New topical form -lower risk of GI effects with equal efficacy

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14
Q

Toradol

A

First injectable

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15
Q

Propionic acid derivatives

A

Ibuprofens
Brand/trade name - Motrin, Advil, nuprin, medipren
Highly protein bound
Drug interactions - increase effects of warfarin, Sulfonamides, certain

16
Q

Cox-2

A

Inflammation and pain
Drug agents Celebrex, relafen,
Contraindicated in patients with salicylate

17
Q

NSAIDs in older adults

A

Assess GI status, renal function, and bp

Prescribed nsaid dose may need to be decreased

18
Q

Steroids

A

Used frequently as an anti inflammatory agent

Not the drug of choice for arthritis due to many side effects

19
Q

DMARDS

A

Immunosuppressive agents
Cancer suppressants Imuran, cytoxan, methotrexate
Immunomodulators
Interleukin receptor antagonists

20
Q

Gout

A

The dx of kings

Disorder of uric acid and purine metabolism

21
Q

Antiinflammstory gout drug

A

Colchacine and newest colcrys

Nursing (10 decks)

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