Chapter 2: Mitosis and Meiosis Flashcards

1
Q

viruses DO NOT

A

contain DNA

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2
Q

an organisms DNA and genes are organized into

A

structures called chromosomes

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3
Q

in eukaryotes genetic continuity of genetic material involves

A

mitosis and meiosis

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4
Q

define chromatin

A

uncoiled chromosomes

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5
Q

prokaryotic cells include

A

bacteria and archaea

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6
Q

eukaryotic cells include

A

protists, plants, fungi, animals

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7
Q

what allowed scientists to see the cell in its highly organized structure?

A

electron microscopy

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8
Q

cell components which are directly or indirectly involved with genetic processes are

A

nucleolus

ribosome

centriole

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9
Q

the nucleolus contains

A
  • rRNA synthesized and initially asembled

- nucleolus organizer region (NOR)

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10
Q

the NOR are portions of

A

DNA that encode for rRNA

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11
Q

the smooth ER is the

A

site of lipid synthesis

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12
Q

the rough ER is the site of

A

protein synthesis

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13
Q

centrioles are

A

cytoplasmic bodies found in centrosomes

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14
Q

centrioles organize

A

spindle fibers

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15
Q

spindle fibers are composed of

A

microtubules consisting of tubulin protein

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16
Q

chromosomes exists as _____ _____ in diploid organisms.

A

homologous pairs

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17
Q

a metacentric chromosome has the centromere located in the ______ of the chromosome.

A

middle

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18
Q

a submetacentric chromosome has the centromere located in the ______ of the chromosome.

A

between the middle and the end

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19
Q

a acrocentric chromosome has the centromere located in the ______ of the chromosome.

A

close to the end

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20
Q

a telacentric chromosome has the centromere located in the ______ of the chromosome.

A

at the end

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21
Q

the haploid number is

A

-half of diploid number

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22
Q

the haploid number constitutes

A

genome of species

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23
Q

what is a karyotype?

A

number and visualization of chromosomes in a cell

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24
Q

what is ploidy?

A

the number of sets of homologous chromosomes in the genome of a cell or an organism

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25
homologous chromosomes have identical
locus
26
which type of chromosomes are not always homologous?
sex-determining chromosomes
27
what is karyokinesis?
genetic material evenly divided into two nuclei
28
what is cytokinesis?
cytoplasmic division
29
the cell cycle is composed of
interphase and mitosis
30
interphase is composed of
G1, S, G2
31
S phase occurs in
nucleus where DNA is duplicated
32
G1 and G2 occurs in
cytoplasm
33
G0 phase is a point where
cells withdraw from cell cycle and enter a non-dividing but metabolically active state (happens in G1)
34
most of the cell cycle is in
interphase
35
the average human completes the cell cycle in
about 16 hours
36
what are the discrete stages of mitosis
``` prophase prometaphase metaphase anaphase telophase ```
37
describe what happens during prophase
chromosomes coil up and condense; centrioles divide and move apart
38
describe what happens during prometaphase
chromosomes move to metaphase plate of cell due to spindle fibers bonding to kinetochores and moving the chromosomes
39
what is cohesion?
a protein complex that holds sister chromatids together
40
what enzyme degrades cohesion?
separase
41
what is shugoshin?
"guardian spirit" that protects cohesion at the centromere while chromosomes are lining up on the metaphase plate
42
describe what happens during metaphase
centromeres of chromosomes are aligned at the metaphase plate
43
describe what happens during anaphase
disjunction occurs; chromosomes migrate to opposite poles
44
what are the 3 things that need to happen for disjunction to be successful?
1. shugoshin is degraded 2. cohesion is cleaved 3. sister chromatids are pulled to opposite ends of the cells
45
describe what happens during telophase
- chromosomes uncoil - nuclear envelope reforms - spindle fibers disappear - nucleolus reforms
46
division of the cytoplasm is known as
cytokinesis
47
what do kinases serve as?
"master control" molecules
48
what binds with kinases?
cyclins
49
what two proteins activate cellular activity
kinases and cyclin
50
the 3 major checkpoints are checked by? where do these checkpoints occur?
- master control molecules (kinases) | - G1, G2, M
51
meiosis maintains
genetic continuity from gen. to gen.
52
meiosis gives rise to genetic variation by
crossing over independent assortment
53
meiosis I is known as the
reductional division
54
meiosis II is known as the
equational division
55
where does crossing over occur?
chiasma (prophase I)
56
what is terminalisation?
when centromeres attach to spindles and nuclear envelope breaks down
57
disjunction is when
half of each tetrad is randomly pulled to opposite poles
58
spermatogenesis begins with
spermatogonium germ cell
59
the spermatogonium becomes
primary spermatocyte
60
primary spermatocyte undergoes mitotic division and produces
haploid secondary spermatocytes
61
secondary spermatocytes undergo
meiosis II
62
oogenesis begins with
oogonium
63
the oogonium enlarges and becomes the
primary oocyte
64
what are the two characteristics to the meiotic division that produce daughter cells during oogenesis?
- receive equal amounts of genetic material | - do NOT receive equal amounts of cytoplasm
65
what receives the bulk of cytoplasm?
the secondary oocyte
66
what is a polar body?
cell with little to no cytoplasm
67
secondary oocyte undergoes secondary division and produces
an ootid and a 2nd polar body
68
secondary division is completed
after fertilization
69
human chromosome 1 is made up of how many nucleotides and genes?
-about 250 million nucleotides 2,000 genes