Chapter 2 - Control of the Internal Environment Flashcards
Homeostasis
maintenance of a constant and “normal” internal environment. (in a resting state)
Steady State
physiological variable is unchanging, but not necessarily “normal”.
-balance between demands placed on body and the body’s response to those demands. (ex. body temp, arterial blood pressure)
Intracellular control systems
- protein breakdown and synthesis
- energy production
- maintenance of stored nutrients
What is a series of interconnected components that maintain a physical and/or chemical parameters at a near constant value? Made up of several components such as; stimulus, sensor/receptor, control center.
Biological Control System
Negative Feedback
Response reverses the initial disturbance in homeostasis.
-most control systems work this way.
Positive Feedback
Response increases the original stimulus (calcium feed forward mechanisms, sodium feed forward mechanisms, inflammation feed forward mechanisms)
Adaptation
change in structure or function of cell or organ system over time.
- results should improve the ability to maintain homeostasis.
- causes your body to more efficiently produce heat shock proteins.
Acclimatization
adaptation to environmental stresses (heat stress in a hot environment)
Cell Signaling
communication between cells or within a cell using chemical messengers.
Intracrine Signaling
chemical messenger inside cell triggers response
Juxtacrine Signaling
chemical messenger passed between two connected cells. (very much so in heart cells).
Autocrine signaling
auto = self
chemical messenger acts on that same cell. (ex. insulin)
Paracrine signaling
chemical messengers act on nearby cells
Endocrine Signaling
chemical messengers released into blood
-only affect cells with specific receptor.
Stress Proteins
Cells synthesize this when homeostasis is disrupted. (heat shock proteins repair damaged proteins in cell)
stressor (exs) -high temperature
- low cellular energy levels
- abnormal pH
-alterations in cell calcium
-protein damage by free radicals (unpaired electron)