Chapter 2 clinicals

Question 1

Rabies Virus

Answer 1

1) Replicates in muscle tissue and then transported RETROGRADE to the cell bodies of neurons
2) Virus replicates in the neuronal cell bodies
- taken up by the terminals of adjacent cells, spreading the infection throughout the CNS
3) virus travels anterograde to the salivary glands

Question 2

Clostridium Tetani

Answer 2

1) Tetanus toxin is transported retrograde-towards neuronal cell bodies