Chapter 2: An integrative approach to psychopathology Flashcards
One-dimensional models
- the assumption that psychopathology is caused by physical abnormality or by conitioning
- attempts to trace the originas of behavior to a single cause
Multidimensional model
- perspective on causality is systematic (world system)
- any influence contributing to psychological health cannot be considered out of context
- biology and behavior of the individual, cognitive, emotional, social and cultural environment affect each other
What are genes?
very long molecular DNA at various locations on chromosomes within the cell nucleus
The nature of genes - what do we knwo about chromosomes?
- each human has 46 chromosomes (23 pairs)
- in each pair one chromosome comes from the father and one from the mother
- Females have two X chromosomes
- Males have one X and one Y (from their father)
What is a defective gene?
- something wrong in the ordering of the molecules (might lead to problems)
Dominant gene vs. recessive gene
- One pair of genes that determines a particular trait.
- Must be paired with another recessive gene to influence a trait.
Most of our development and most of our behavior, our personality, and intelligence are …
POLYGENIC: influenced by many genes, each contributing only a tiny effect, all of which, may be influenced by the environment.
What is a genome?
an individual’s complete set of genes
20.000 - 25.000)
What are two sophisticated procedures that allow to look for patterns of influence across many genes?
- Quantitative genetics
- Molecular genetics
Quantitative genetics
- estimates the effects of genes in explaining individual differences (heritability)
- without necessarily telling us which genes are responsible for which effects
Molecular genetics
- focuses on examining the actual structure and functioning of genes
- with increasingly advanced technologies (such as DNA microarrays)
What did Eric Kandel (1983) propose?
- proposed that learning may cause changes in the genetic structure of cells,
- leading to alterations in the brain’s biochemistry and receptor numbers
- brain is plastic (can change in response to environmental influences)
Psychopathology is explored in the context of gene-environment interactions through two models - which ones?
- Diasthesis-Stress model
- Reciprocal Gene-Environment model
Diathesis-Stress Model (tells us what?)
- Individuals inherit tendencies (diatheses) from multiple genes, making them susceptible to developing certain traits or behaviors
- Tendencies or vulnerabilities only manifest when exposed to specific environmental stressors.
- Gene-environment interactions can lead to the development of mental disorders.
What was the study from Caspi et al. (2003) about and what did they find?
- explored gene-environment interactions relation to depression
- Individuals with two copies of short allele (SS) were more suseptible to depression under stressful life events (childhood maltreatment)
- than those with the copies of the two long allele (LL)
Reciprocal Gene-Environment Model (What does this model tell us?)
- Genetic endowment may increase the likelihood of experiencing stressful life events.
- Individuals with a genetic vulnerability to a disorder may exhibit certain personality traits or behaviors that lead them to create environmental risk factors triggering the genetic vulnerability.
- suggests that genes can influence the environment individuals create for themselves.
What is neuroscience?
knowing how the nervous system and, especially, the brain work is central to any understading of our behavior, emotions, and cognitive processes.
The human nervous system includes …
the central nervous system (CNS)
- consisting of the brain and the spinal cord,
and the peripheral nervous system (PNS)
- somatic nervous system (SNS) and the autonomic nervous system (ANS)
What does the central nervous system (CNS) do?
- processes information from sense organs and responds accordingly
- sorting out relevant info from irrelvant stimuli and initiating appropritae reactions
Neurons have a cell body with two types of branches (which two?)
- dendrites
- axons
What do dendrites do?
receive chemical impulses from other nerve cells and then convert them into electrical impulses
What do axons do?
- transmit electricalimpulses to other neurons
-forming connections to a highly complex network