Chapter 19 - Lab And Clinical Procedures Flashcards
Cytogenetic analysis
Chromosomes of normal or tumor cells are examined for breaks, translocations, or deletions of DNA
Immunohistochemistry
Localization of antigens or proteins in tissues using labeled (colored or fluorescent) antibodies
Protein marker tests
Measure the level of proteins in the blood or on the surface of tumor cells. It can diagnose the type of cancer.
Bone marrow biopsy
Aspiration of bone marrow tissue and examinations under a microscope for evidence of malignant cells
Bone marrow or stem cell transplantation
Bone marrow or stem cells are infused intravenously into a patient
Autologous marrow transplantation
- Marrow previously obtained from patient and stored is re-infused when needed
- Infusion of patient’s own bone marrow or stem cells after a course of chemotherapy and/or radiation therapy.
Allogeneic marrow transplantation
- Marrow is obtained from a living donor other than the recipient
- bone marrow transplant uses bone marrow from a donor
Peripheral blood stem cell transplantation
- Immature blood cells called stem cells are selected and harvested from the blood of a patient instead of from the bone marrow.
- After undergoing chemotherapy, the patient gets reinfusion of the stem cells to repopulate the bone marrow with blood cells
Core needle biopsy
Insertion of a large-bore needle into tissue to remove a core of cells from microscope examination.
Exfoliative cytology
- Cells are scraped from the region of suspected disease and examined under a microscope.
- The Pap test (smear) is an example
Fiberoptic colonoscopy
Visual examinations of the colon using a fiberoptic instrument
Laparoscopy
Visual examination of abdominal cavity using small incisions and a laparoscope.
Mammography
X-ray examination of the breast to detect breast cancer
PET-CT scan
Diagnostic procedure combining CT (computed tomography) and PET (positron emission tomography)
Radionuclide scans
Radioactive substances (radionuclides) are injected intravenously and scan (images) of organs are obtained.