chapter 19 - diuretics Flashcards
A patient with cerebral Adema would benefit best from which group of diuretic agents?
Osmotic diuretics
A patient with MILD hypertension would be prescribed to what type of diuretic?
Thiazide
Osmotic diuretics function by doing what?
Blocking reabsorption of NaCl in the:
Proximal tubule
And
Defending limb of the loop of henle
The 3 most common adverse reactions to diuretics are?
Hypovolemia
Electrolyte abnormalities
Acid base abnormalities
Diuretics that produce their effects by inhibiting the reabsorption of chloride and sodium in the ascending limb of the loop of Henle are known as?
Loop diuretics
What is a common potassium sparing diuretics?
Spiranolactone
What is the most commonly selected osmotic diuretic agent?
Mannitol
Carbonic anhydrase inhibitors exhibit their effects on what part of the kidneys and what on solutes?
On the proximal tubule
Reducing Na and bicarb
Loop diuretics reabsorb what solutes and at what part of the kidneys?
sodium, potassium, and chloride
from the ascending loop of henle.
Thiazide diuretics cause what in the kidneys?
Inhibition of NaCl reabsorption in the distal tubules
What is the mode of action of spironolactone?
Competitively blocks actions of aldosterone in cortical collecting ducts
Furosemide(Lasix), bumetanide, torsemide are what kind of diuretics?
Loop diuretics
What are the two indications for osmotic diuretics?
Treat acute renal failure and reduce intracranial and intraocular pressure
What do loop diuretics cause?
Acute vasodilation,
decrease in pulmonary capillary wedge, blood pressure, systemic vascular resistance