Chapter 18 Flashcards
1
Q
Where/how does aldosterone act?
A
Proximal convoluted tubule - increased sodium retention
DCT - increases sodium retention in exchange for potassium
2
Q
What proportion of cortisol producing adrenal tumour are malignant?
A
50%
3
Q
What is the sex predisposition of AD-HAC?
A
70% female
4
Q
What is the sensitivity of the ACTH stimulation test?
A
PD - 80%
AD - 60%
5
Q
What is the sensitivity of the LDDST?
A
95%
6
Q
What are the expected LDDST findings for normal dogs, or dogs with hAC, iHAC, PD-HAC and AD-HAC?
A
pg 358
7
Q
How can eACTH be misleading?
A
Sample handling can cause low eACTH
Low eACTH reported in PDH (but high not in ADH)
8
Q
How does elevated cortisol affect T4 and through what mechanism?
A
Reduced by 70%
Inhibition of pituitary secretion of TSH
9
Q
What % cats with HAC have DM at diagnosis?
A
80%
