Chapter 17 Flashcards
Olfactory epithelium (size,where,what cells)
Total area: 5cm^2
Superior part of nasal cavity covering surface of cribiform plate and extending along the superior nasal concha
Olfactory receptor/supporting/basal cells
Olfactory receptors cells
(1st order?, shape, how many total/functional types)
1st order neurons
Bipolar N with exposed knob shaped dendrite and an axon projecting through cribriform plate that ends in an olfactory bulb
10 million/400 functional types
Olfactory cilia (where, function)
Extends from olfactory receptor
Site of transduction (stimulus->GP)
Olfactory receptor proteins (where, function)
Within PM of olfactory cilia
Detect inhaled chemicals
Odorants
Chemicals that bind and stimulate the olfactory receptor in olfactory cilia
Olfactory Supporting cells (what/where, function)
Columnar epithelial cells of MM lining of nose
Provide physical support, nourishment, electrical insulation for O receptor and detoxify chemical that contact O epithelium
Basal cells (what/where, function)
Stem cells between bases of supporting cells
Undergo cell division continuously
How long do O receptors live for
2 months
Olfactory glands AKA?
Bowman’s glands
Olfactory glands (where, function)
Within CT supporting O epithelium
Produce mucus carried by ducts to moisten surface, dissolve for transduction
What are all O cells/glands innervated by
By psymp N within branches of facial (VII) nerve
What do impulses in the facial nerve also stimulate (also what stimulates them)
Stimulated by chemicals
Also stimulates lacrimal glands and nasal mucous glands (tears/runny nose)
Olfactory adaptation
Rapidly: about 50 percent in the first second but slowly after
5 taste types
Salty sour sweet bitter umami
What is salty
Na+
What is sour
H+
What is sweet
Sugars
What is bitter
Caffeine, morphine, quinine, poison, etc
What is umami
Amino acids
Taste buds (what, 3 cells)
Oval body consists of:
Supporting cells
Gustatory receptor cells
Basal cells
Gustatory receptor cells number
About 50
What projects through G receptor cells
G microvilli project though each GRC through taste pore
GRC lifespan
10 days
Papillae (what is in them, function, types)
Taste buds in these, increas SA and have rough texture
Vallate
Fungiform
Foliate
Filiform
Vallate/circumvallate papillae (number/size,where/#taste buds)
12 very large
Inverted V at back of tongue
100-300 taste buds
Fungiform papillae (shape, where, taste buds)
Mushroom shaped all over tongue
About 5
Foliate papillae (where, taste buds)
In small trenches on lat margins of tongue
Most TB degenerate in early childhood
Filiform Papillae (where, taste buds)
Entire tongue
Tactile receptors increase friction
NO TB
Tastents
Chemical that stimulate GRC
Gustatory pathway
Tastant dissolved = contact with PM of G microvilli (transduction) = demoralizing receptor potential= stimulates Exocytosis of synaptic vesicles from GRC = liberated NT molecules trigger GP = NI in 1st order that synapse with GRC
How does receptor potential arise for different tastants?
Na+/H+: enter GRC via Na+/H+ channels in PN= depolarization= NT release
Other: don’t enter GRC rather bind to receptors on PM linked to G proteins = activates enzymes that produce 2nd messenger = depolarization = NT release
Taste thresholds least to most
Bitter sour sweet/salty
Gustatory adaptation
Complete adaptation in 1-5 min of continuous stimulation
External outer ear parts
Auricle
External auditory canal
Eardrum
Auricle/pinna (what/parts)
Flap of elastic cartilage
Helix:rim
Lobule: inferior portion
External auditory canal
Curved tube 2.5 cm long in temporal bone
Tympanic membrane
Eardrum
Semitransparent partition between external auditory canal and middle ear