Chapter 17 Flashcards
Acute illness
Disease or illness that is characterized by a sudden onset and limited duration
Chronic disease
Condition or illness that is characterized by long in some cases to find as greater than six months or permanent duration
Cognitive disability
Condition that involves impairment in intellectual activities such as thinking reasoning and remembering
Nosocomial infection
An infection inquired in a hospital or other healthcare facility that is usually caused by viruses, bacteria, or fungal pathogens
Physical disability
Physical condition that impairs, interferes with, or limits of persons ability to engage in certain task or actions or to participate in typical daily activities and interactions
Physical health
Refers to the conditions of the body or body systems, a continuum of health, lack of disease, or disability to states of acute or chronic illness, disability, or disease
Sensory disability
Condition that involves sensory organs, such as eyes, ears, or skin (touch)
Headaches and migraines
Migraine headaches especially related to menstruation may have a reduction in frequency and severity during pregnancy and lactation. Some evidence of lactational headaches associated with let down an over full breath. Common drugs that are compatible with breast-feeding include propranolol and nonsteroidal anti-inflammatory drugs.
Infectious diseases
Common cold and the flu are caused by viruses. They do not affect the ability to breast-feed. Parents should beware of decongestant containing pseudoephedrine because it can reduce milk production particularly in parents with poor or marginal milk. If antibiotics are needed for bacterial infection healthcare providers should use clinical guidelines for appropriate choices, dosing and duration of treatment.
Urinary track infection is the most common problem in women
Can be treated well with sulfamethoxazole and trimethoprim
Methicillin resistant staph infections (MRSA) is an antibiotic resistant infection they can either be hospital or community acquired
If a breast-feeding parent becomes infected breast-feeding and express milk should be withheld for 24 hours while antibiotic therapy is initiated. MRSA and other nosocomial infections in the newborn can be decreased by exposure to nontoxic bacterial flora via skin to skin contact after birth.
Group B streptococci (GBS) are leading cause of neonatal sepsis, is a common cause of neonatal morbidity and mortality
Treated with antibiotics it discovered prenative or intrapartum. If present in the vagina or rectal area can colonize the nasopharynx of the newborn during birth. Where can acquire GBS from breastmilk. Milk can be cultured and parent treated and continue breast-feeding
Tuberculosis
Not common and develop countries but very prevalent and developing countries. Parents who have tuberculosis at time of birth and appropriately treated with isoniazid can breast-feed. If tuberculosis is discovered at the time of birth it is necessary to separate the parent and infant for two weeks. Parent must initiate therapy and expressed milk to protect milk production. Issiazid is secreted into milk but levels are considered safe. Breast-feeding should be withheld for two hours after drug administration to avoid peak plasma concentrations
Zika virus spread by species of mosquitoes can be transmitted to the fetus during pregnancy and can cause congenital Zika fever with defects of the skull being the most common result
Human milk spread has not been confirmed although shedding of Zika virus material may be in the milk. Mothers who have suspected, probable, or confirm secret virus infection or travel to areas where Zika virus is endemic can breast-feed their infants.
Ebola virus characterized by fever, severe headache, muscle pain, weakness, fatigue, diarrhea, vomiting, abdominal pain, and unexplained hemorrhage.
Spread by close contact. Parents who are infected should not breast-feed. Decision about feeding the infant of a parent who is infected or has been infected must be weighed carefully. If there is no safe alternative to the parents milk the parent may have to breast-feed
HIV
HIV is classified as a retrovirus. Group of RNA viruses that insert a DNA copy of their genome into the host cell in order to replicate. When left untreated HIV infection results in the distraction of T cell immunity that allows recurrent, severe, and ultimately life-threatening opportunistic infections that manifest as aids. Spread by exchange of infected blood or by mucous membrane contact with infected blood and body fluids. In infants and small children most parent to child transmissions occur either pair of Natalie or through breast-feeding. HIV infected parents in high resource countries have been encouraged to avoid breast-feeding. Resource poor countries recommend exclusive breast-feeding for six months along with antiviral therapy for the mother and the baby. Perinatal HIV infection have dropped dramatically in the United States due to routine HIV screening in the use of a RT for the control and prevention of maternal infection, elective cesarean section and HIV positive women and avoidance of breast-feeding.
Asthma
In the US the prevalence of asthma among pregnant women is 3.7 to 8.7%. Exclusive breast feeding offers protection for infants and families with a history of asthma. Lactation should not be interrupted for asthmatic parents. Corticosteroids administered through metered dose inhaler‘s avoid systemic effects by delivery medication directly to the lungs. Bronchodilation are used to manage acute exacerbation’s.
Diabetes mellitus
Impaired carbohydrate metabolism is the Hallmark. Type one diabetes can occur pre-pregnancy in which insulin is not produced by the beta cells of the pancreas. Breast-feeding should be encouraged because colostrum helps to stabilize the Newports blood glucose. Parent and infant can experience local close levels after birth and must be monitored closely. Colostrum express prenatally can later referred to the hypoglycemic infant of a diabetic parent. If infant is admitted to neonatal intensive care milk expression should begin immediately. Insulin therapy is continued after giving birth. Insert it safe during lactation because it is such a large molecule. Delayed lactogenesis about one day may occur. Supportive practices such as early and continued skin to skin contact, rooming in, and feeding on cue can offset some of the factors. Diabetic parents may be at higher risk for mastitis and candiadiasis especially if they have elevated blood glucose levels.
Type two diabetes this is when there is impaired response to insulin and beta cell dysfunction
Can be part of the metabolic syndrome characterized by hypertension, obesity, dyslipidemia and polycystic ovary syndrome. It is much more common during pregnancy today due to higher obesity rate. Patients with type two diabetes are less likely to breast-feed. Metforman is often used to treat type two diabetes during and after pregnancy. Type two diabetes is associated with postpartum low milk production. May have a shorter duration of breast-feeding.
Gestational diabetes is a glucose intolerance that occurs during pregnancy. It occurs in an estimated 9% of all pregnancies in United States
Are less likely to breast-feed the non-diabetic counterparts. Breast-feeding should be encouraged because lactation improves the maternal metabolism of glucose and may prevent type two diabetes. Delayed lactogenesis can occur in parents with gestational diabetes which may be up to 1/3. Support is essential for parents as noted with type one and type two diabetes.
Thyroid disorders - Hypothyroidism
Hypothyroidism: thyroid function is imperative to maintaining A pregnancy. Symptoms include thyroid swelling or nodules, cold intolerance, dry skin, thinning hair, poor appetite, extreme fatigue and depression. Can result in low milk production. Thyroid supplementation is safe with breast-feeding. If diagnosed postnatal he will likely experience symptom release and increase milk production. If take thyroid supplements during pregnancy should be reevaluated in the postpartum. Because medication doses could likely be reduced to the pre-pregnancy level.
Hyper thyroidism
Occurs in the first postpartum year in 9% of women. Graves disease accounts from 95% of cases of hyperthy organism during pregnancy and only zero. 2% of cases post Natalie. Lactation is not usually impacted by hyperthyroidism. Anti-thyroid medication‘s are considered safe during lactation. However doses should be low to moderate because of concerns of hepatotoxic
Postpartum thyroiditis
Most common thyroid disorder. It affects 1.1 to 16.7% of women in the first year after birth. Believed to be an auto immune disorder. Includes fatigue, depression, and anxiety. May manifest is hyper thyroidism or hypo thyroidism or I can begin as hyperthyroidism and progressed to hypothyroidism. Need radioactive iodine uptake testing to actually make diagnosis which requires temporary breast-feeding interruption.
Pituitary dysfunction
Postpartum hemorrhage and hypotension can increase the pituitary gland to cease production of gonadotrophins leading to panhyppituitarism or Sheehan syndrome. Symptoms include lactation failure, loss of pubic and axillary hair, cold intolerance, breast and vaginal tissue atrophy, low blood pressure, secondary hypothyroidism, and adrenal failure. In severe cases the symptoms can occur and progress over the years.
Cystic fibrosis
Hereditary autosomal recessive genetic disorder involving the cystic fibrosis transmembrane regulator gene on a chromosome seven. Affects the apical membrane of epithelial cell lining the airways, biliary tree, intestines, vas deferens, female reproductive tract, sweat ducts, and pancreatic ducts. Highest prevalence is in North America and lowest is in Africa and Asia. Research indicates that affected individuals may or may not have increased morbidity during pregnancy and lactation. However pregnant and lactating mothers with cystic fibrosis have increased need for pulmonary and nutritional status monitoring and treatment. Many parents with cystic fibrosis choose to breast-feed and should be supported. Human milk is not adversely affected by cystic fibrosis. Most medication’s are compatible with breast-feeding those summer contraindicated.
Polycystic ovary syndrome (PCOS)
Common endocrine disorder in women that is characterized by abnormal ovulation, clinical or laboratory indices of increased androgen levels, and polycystic ovaries. Prevalence is between four and 6%. Infertility among women with PCOS is common and breast-feeding can be challenging. Observe breast shape variations including tubular shape, large separation, and large nipples with little change in breast size during pregnancy an insufficient milk production among women with PCOS. Insulin resistance and compensatory hyperinsulinemia are hallmarks of PCOS putting women at increased risk of impaired glucose tolerance and type two diabetes. 40% of women with PCOS developed impaired glucose tolerance and 10% develop diabetes by age 40. Metformin is the drug of choice for PCOS. Metformin is safe for breast-feeding. PCOS is a complex disorder with many characteristic variations. Parents need support.
Auto immune diseases, inflammatory bowel disease
Two major forms of inflammatory bowel disease are ulcerative colitis and Crohn’s disease. Breast-feeding rates in this group are reported to be lower than the general population. Often related to concerns about safety of prescribed medications and transferred infant. Breast-feeding does not impact disease activity of either disease, breast-feeding should be encouraged. Majority of medication use particularly Biologics are considered probably compatible with breast-feeding although methotrexate is considered teratogenic and should not be used during pregnancy or lactation.
Systemic lupus erythematous
Audio immune disorder that affects multiple body systems and occurs frequently during childbearing years. Manifested diversely and can include headache, arthritis symptoms, butterfly rash on my chest and knows. Raynaud phenomenon, fatigue and myalgia. Miscarriage and prematurely rates are higher among women with lupus. About half of the women in a sample of 51 pregnancies breast-fed their infants. Low postpartum lupus activity, term delivery and a plan to breast-feed early in pregnancy where is associated with Breastfeeding. Breastfeedingg should be encouraged. Research suggests that hydroxychloroquine, azthioprine, methotrexate and prednisone have very limited transfer into milk. However some experts do not recommend methotrexate. Special considerations for joint pain and swelling and Raynaud phenomenon should be considered
Multiple sclerosis
Degenerative neurological disorder that is immune mediated, the myelin sheath covering the nerves is attacked by the immune system. Four disease courses include clinically isolated syndrome, relapsing remitting multiple sclerosis, secondary progressive multiple sclerosis, and primary progressive multiple sclerosis. Symptoms include weakness, fatigue, in coordination, paralysis, and speech and visual disturbances. More common among women and often diagnosed during reproductive years. Risk of relapse decreases during pregnancy but increases in the postpartum period as much as 70% particularly during the first 3 to 4 minutes. Now appears the breast-feeding reduces the risk of multiple sclerosis relapses. Evidence is growing for the safe use of DMARD‘s for multiple sclerosis. A pregnancy may not be powerful enough to suppress the risk of rebound relapses. Exclusive breast-feeding is an option for many women who want to do so but in cases of high disease activity and those women who do not want to breast-feed early re-introduction of MS therapies should be considered. Breast-feeding for four months or longer protects the infant against multiple sclerosis. This advantage should be discussed with parents who have multiple sclerosis and choose to breast-feed.
Rheumatoid arthritis
Chronic inflammatory disease presumably caused by a genetically influenced auto immune response the damages the synovial lining of the joints. Symptoms include pain, swelling, and stiffness of the joints, damage and deformity of the joints, fatigue, and decreased mobility. Can’t start in early childhood and last lifetime. Characterized by flares and remissions and disease activity. Women are disproportionately affected by this disease. Fertility can be diminished in women with rheumatoid arthritis. For some women when pregnant disease activity is sometimes decreased. Rheumatoid arthritis flare or more common in the postpartum. Likely due to multiple hormonal and immunologic changes during pregnancy. Some anti-rheumatic drugs are not compatible with pregnancy but can be used for lactation answered should be stopped before 32 weeks of gestational age due to risk of premature closure of ductus arteriosus in the fetus and labor impairment in the mother. And some are compatible with breast-feeding. Non-fluorinated glucocorticoid, sulfasalazine at low doses hydroxychloroquine and tumor necrosis factor inhibitors are compatible with pregnancy and breast-feeding. DMARD such as methotrexate are not recommended during pregnancy or lactation due to teratogenic status. Limited information on Biologics so not recommended in Pregnancy or Lactation. There really isn’t much evidence on support for mothers who wish to breastfeed with rheumatoid arthritis. Support to relieve fatigue in general and physical bracing to support affective joints may be particularly helpful for breast-feeding mothers.