Chapter 15 - Acid/base Balance Part 1 Flashcards

1
Q

Internal pool

A

The quality of any particular substance in the ECF
-input must balance the output

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2
Q

input

A

Ingestion, metabolic consumption
-substances into plasma is poorly controlled
-eating habits are variable

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3
Q

Output

A

Excretion, metabolic consumption
-compensatory adjustments usually occur on output side by urinary excretion

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4
Q

Positive balance vs negative balance

A

Positive balance- input exceeds output

Negative balance- output exceeds input

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5
Q

___ is the most abundant substance in the body

A

Water

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6
Q

ICF

A

Found inside cells

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7
Q

ECF

A

Found outside cells
-interstitial fluid or plasma

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8
Q

Body fluid

A

Extracellular 33p

Intracellular 67p

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9
Q

Extracellular

A

Interstitial fluid 75p

Plasma 25p

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10
Q

Minor ECF components

A

Lymph, transcellular fluid

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11
Q

Barrier between ECF and ICF

A

Cellular plasma membranes and blood vessels
-major differences between ECF and ICF

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12
Q

ECF serves as

A

An intermediary between the cells and external environment

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13
Q

The body looks after the ECF via

A

Kidney function
-volume
-osmolarity

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14
Q

ECF fluid volume affects

A

Blood pressure control

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15
Q

ECF fluid osmolarity affects

A

Cell volume
-shape

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16
Q

Maintains salt balance is very important in long term regulation of

A

ECF volume

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17
Q

Maintains water balance is very important in regulating

A

ECF osmolarity

18
Q

Salt input occurs by

19
Q

Salt balance is maintained by

A

Outputs in urine

20
Q

Kidneys aim to

A

Keep salt constant in ECF

21
Q

Adjust the amount of salt excreted by controlling

A

-glomerular filtration rate
-tubular reabsorption of sodium

22
Q

Long term regulation of ECF volume and blood pressure

A

Control volume by controlling Na

23
Q

ECF and ICF have same ___ despite…

A

Osmolarity, large chemical differences

24
Q

If fluid outside cell has same osmolarity

25
If fluid outside cell has higher osmolarity
Hypertonic
26
If fluid outside cell has lower osmolarity
Hypotonic
27
What is accountable for the ECF’s osmotic activity
Sodium
28
What is accountable for the ICF’s osmotic activity
K+
29
Deficit of free water in ECF
Osmolarity becomes too hypertonic -too concentrated -dehydration
30
Excess of free water in ECF
Osmolarity becomes hypotonic -doo dilute -overhydration
31
Hypertonic it’s
Excessive concentration of ECF solutes -cells tend to shrink -excessive water loss, or insufficient water intake -diabetes insipidus
32
‘Symptoms of hypertonicity
-shrinking of brain neurons -circulatory disturbances -dry skin, sunken eyes, dry tongue
33
hypotonicity
-usually excreted in urine -cells tend to swell -water rapidly digested, kidneys can’t respond quick enough
34
Hypotonicity symptoms
-swelling of brain cells -weakness -circulatory disturbances -excess free water = water intoxication
35
Output insensible loss
Lungs, non sweating skin
36
Output sensible loss
Sweating, feces, urine excretion -aware of but not neccesarily controlled
37
Where is vasopressin produced
Heurosecretroy neuronal cell bodies in hypothalamus
38
Where is vasopressin released
Neuronal terminals in posterior pituitary
39
Hypothalamic osmoreceptors
Located near vasopressin secreting cells and thirst centre
40
Osmolarity increases (hypertonic ECF)
Increased vasopressin secretion and thirst stimulated
41
Osmolarity decrease (hypotonic ECF)
Vasopressin secretion decreased and thirst suppressed