Chapter 15 - Acid/base Balance Part 1 Flashcards
Internal pool
The quality of any particular substance in the ECF
-input must balance the output
input
Ingestion, metabolic consumption
-substances into plasma is poorly controlled
-eating habits are variable
Output
Excretion, metabolic consumption
-compensatory adjustments usually occur on output side by urinary excretion
Positive balance vs negative balance
Positive balance- input exceeds output
Negative balance- output exceeds input
___ is the most abundant substance in the body
Water
ICF
Found inside cells
ECF
Found outside cells
-interstitial fluid or plasma
Body fluid
Extracellular 33p
Intracellular 67p
Extracellular
Interstitial fluid 75p
Plasma 25p
Minor ECF components
Lymph, transcellular fluid
Barrier between ECF and ICF
Cellular plasma membranes and blood vessels
-major differences between ECF and ICF
ECF serves as
An intermediary between the cells and external environment
The body looks after the ECF via
Kidney function
-volume
-osmolarity
ECF fluid volume affects
Blood pressure control
ECF fluid osmolarity affects
Cell volume
-shape
Maintains salt balance is very important in long term regulation of
ECF volume
Maintains water balance is very important in regulating
ECF osmolarity
Salt input occurs by
Ingestion
Salt balance is maintained by
Outputs in urine
Kidneys aim to
Keep salt constant in ECF
Adjust the amount of salt excreted by controlling
-glomerular filtration rate
-tubular reabsorption of sodium
Long term regulation of ECF volume and blood pressure
Control volume by controlling Na
ECF and ICF have same ___ despite…
Osmolarity, large chemical differences
If fluid outside cell has same osmolarity
Isotonic