Chapter 14 (Part 2) Flashcards
why would we call funny channels funny? isn’t that kind of rude?
no, it’s just because they let “in” K+ as well as Na+
what molecule regulates funny channels?
cAMP
don’t forget your yellow chart thing!
okay thank you!
delaying repolarization delays the next contraction. the muscle contraction and relaxation time..
takes as long as the refractory period lasts
why are exchangers the way they are?
minimizing the effect of kicking Ca out of SR and muscle cell by bringing a similar charge in
why is the plateau phase important?
- creates a refractory period to delay of another action potential
- refractory period during plateau phase prevents summation or tetanus
plateau phase: summation
summation would result in another immediate contraction -> rapid and shallow heart beats. refractory period prevents that.
plateau phase: tetanus
sustained contraction without relaxation. this can cause the heart to miss the next AP, cardiomyocytes get out of sync, and the heart can stop beating.
what can happen when the heart misses an AP?
cardiomyocytes get out of sync, and the heart can stop beating.
ECG graph: P wave
generated when atria are full and SA node fires; electrical signal spreads throughout the atria causing depolarization
ECG graph: P-Q segment
time it takes for an AP to travel from the SA node to the AV node
ECG graph: QRS (2)
marks the firing of the AV node and depolarization of ventricles
includes depolarization of intraventricular septum, and throughout the ventricles
ECG graph: atrial repolarization
occurs during the QRS segment, but its electrical activity is masked by the stronger ventricular electrical activity
ECG graph: S to T segment
reflects the plateau (L-type Ca+2 channels are open) in myocardial AP
ventricles contract and pump blood out into the pulmonary and general circulation
ECG graph: T wave
represents ventricular repolarization