Chapter 11 (Part 2) Flashcards
what are the two major types of acetylcholine receptors?
nicotinic receptors
muscarinic receptors
muscarinic cholinergic receptors are coupled to ?
G proteins
nicotinic cholinergic receptors are coupled to ?
ionotropic
adrenergic receptors exist as either ?
alpha or beta receptors
binding to alpha adrenergic receptors means ? (3)
- increase blood pressure
- decrease circulation to GI tract and kidneys to provide more blood flow to skeletal/cardiac muscles
- results in increased blood return to the heart
binding to beta adrenergic receptors means ? (3)
- increase heart rate and heart contraction force
- dilation of bronchial airways of the lungs
- dilate skeletal muscle blood vessels and cardiac coronary arteries
what is the goal of the autonomic nervous system synapse?
stimulate multiple target cells at once
what do autonomic neurons have instead of axon terminals?
varicosities along each collateral axon
what is the significance of varicosities in the autonomic neurons?
target a large surface area on a gland or smooth muscle by raining down NTs
what are two drugs that can be used to manipulate the autonomic nervous system?
agonist and antagonist
what is an agonist?
compound that binds to the same receptor as a natural signaling molecule; elecitis same effect as the natural signaling molecule
what is an antagonist?
compound that binds to the same receptor but does not trigger an effect; blocks the effect of natural signaling molecule
name an example of a commonly used acetylcholine antagonist?
atropine
how is atropine commonly used?
in eye exams
name a place we might find a1 adrenergic receptors?
nasal blood vessels