Chapter 14- Neurocognitive Disorders Flashcards
Amnestic Disorder
Striking deficit in the ability to recall ongoing events more than a few minutes after they have taken place, or the inability to recall the recent past.
Alzheimer’s Disease
A progressive and fatal neurodegenerative disorder that is characterized by deterioration in memory, cognition, and basic self-care skills.
Amyloid Plaques
Found in the brains of people with Alzheimer’s disease, these deposits of aluminum silicate and abnormal protein (beta amyloid) are believed to cause loss of neurons.
Anterograde Amnesia
Loss of memory for events that occur following trauma or shock.
APOE-E4 Allele
Variant of a gene on chromosome 19 that significantly enhances risk for late onset Alzheimer’s disease.
Delirium
State of mental confusion characterized by relatively rapid onset of widespread disorganization of the higher mental processes, caused by a generalized disturbance in brain metabolism. May include impaired perception, memory, and thinking and abnormal psychomotor activity.
Dementia
Progressive deterioration of brain functioning occurring after the completion of brain maturation in adolescences. Characterized by deficits in memory, abstract thinking, acquisition of new knowledge or skills, visuospatial comprehension, motor control, problem-solving, and judgment.
Early-Onset Alzheimer’s Disease
Form of Alzheimer’s disease that appears in people who are younger than approximately 60 years of age. Thought to be caused by rare genetic mutations.
HIV-Associated Neurocognitive Impairment
Mild or major neurocognitive disorder caused by infection with the human immunodeficiency virus (HIV).
Huntington’s Disease
A rare and fatal degenerative disorder which is manifested in jerking, twitching movements, and mental deterioration. Caused by a dominant gene on chromosome 4. Formerly called Huntington’s chorea. Patients usually develop dementia.
Korsakoff’s Syndrome
This disorder, also referred to as Korsakoff’s dementia, Korsakoff psychosis, or amnesic-confabulatory syndrome, is a neurological condition resulting from chronic alcohol abuse and severe malnutrition (vitamin B).
Late-Onset Alzheimer’s Disease
The occurrence of Alzheimer’s disease in the more elderly. One gene thought to be involved in this form of Alzheimer’s disease is the APOE gene.
Major Neurocognitive Disorder
A new DSM-5 diagnosis, this involves severe impairment in cognitive functioning that reflects a significant decline from the persons previous level of performance. The problems in cognitive functioning create problems for the person in terms of their ability to perform routine activities.
Mild Neurocognitive Disorder
A new DSM-5 diagnosis that is characterized by a modest decline in cognitive functioning that does not interfere with the person’s ability to perform the routine tasks.
Neurofibrillary Tangles
Twisted and weblike nerve filaments that characterize the brains of patients with Alzheimer’s disease.