Chapter 14 - Brain Flashcards
What is the function of CSF?
- Buoyancy - floats brain so that it doesn’t crush under its own weight
- Protection - protects brain from bumping into cranium during jolting movement
- -Concussion is a case of failed brain protection! - Chemical Stability - carries metabolic waste –> filters it through kidneys –> reabsorbed into blood plasma)
Where is CSF made?
CSF is made by Ependymal cells in the…
- -Choroid plexus (in each ventricle)
- -Subarachnoid space
Describe the the pathway of CSF
Lateral ventricles –> third ventricle –> fourth ventricle –> subarachnoid space –> dural sinus –> *circulatory system (heart + lungs) –> choroid plexuses (reabsorbs CSF as blood plasma)
What are the four fluid-filled chambers in the brain?
Ventricles - four chambers containing CSF
Lateral ventricles (2)
Third Ventricle
Fourth Ventricle
Regulates the entry of substances into the brain (blocks potentially harmful substances…toxins, pathogens, etc.)
Blood Brain Barrier (BBB)
Where is the Blood Brain Barrier missing + why?
BBB missing in…
- -Circumventricular organs (CVOs)
- -Third + Fourth ventricles - route for HIV invasion!
Why?
–These locations must monitor physiological conditions (glucose, pH, osmolarity, etc.)
What three brain parts are considered to be the brain stem?
- Midbrain
- Pons
- Medulla oblongata
Nuclei that extend up through the brainstem and into the midbrain
Recticular formation
What important physiological functions are controlled by the reticular formation?
- Somatic motor control - muscle tone, balance, posture, breathing, etc.
- Cardiovascular control
- Pain modulation - descending analgesic (painkiller) pathways block pain transmission
- Sleep/Consciousness - controls alertness
- -Reticular activating system - arouses + maintains consciousness - Habituation - learning to ignore repetitive stimuli
What is the corpora quadrigemina?
Tectum - contains the corpora quadrigemina (4 baby bodies)
- -Superior colliculi (2) - visual attention + “eye tracking”, involved in reflex response
- -Inferior colliculi (2) - receives signals from inner ear, involved in balance + hearing`
A region of gray matter on either side of the cerebral aqueduct in the midbrain.
Tegmentum
Dorsal part of the midbrain
Tectum
What are the parts of the Tegmentum?
- Red nucleus - fine motor control (along w/ cerebellum)
- Substantia nigra - sends inhibitory signals –> thalamus
- -Prevents unwanted body movements
- -Degeneration of this = muscle tremors
What are the three parts of the Diencephalon? What do they do?
- Thalamus “Gatekeeper” - filters stimuli + relays signals from cerebellum –> cerebrum
- -Involved in senses - Hypothalamus “Master Gland” - controls ANS and endocrine system
- -Involved in hormones, heart rate, BP, thermoregulation - Epithalamus (Pineal Gland) - controls diurnal rhythms
- -Involved in production of melatonin, and ultimately sleep
What does the Cerebellum control?
Complex movements (motor control, “muscle memory” etc.)
What are the consequences to injury of the Cerebellum?
- -Cerebellar lesions - deficit in coordination, locomotion, linguistics, emotions + non-motor functions like difficulty planning
- -Small cerebellums - related to ADHD in children
Worm-like structure that separates the cerebellum into two hemispheres
Vermis
What is the function of the Vermis?
Maintains equilibrium