Chapter 12: Body Water and Electrolyte Homeostasis Flashcards
Whole blood
Plasma (55%), buffy coat (<1%), erythrocytes (45%)
Plasma
Composed of water, ions, and macromolecules such as fibrinogen and other proteins
Serum
Liquid part if blood remaining after a clot has formed; lacks the protein fibrinogen and other clotting factors
Anion gap
Difference between the sum of measured cations and the sum of measured anions
Osmolarity
Concentration per volume of solution, where 1 osmolar solution contains 1 osmol/L of solution
Osmolality
Solution concentrations expressed on a weight factor are temperature independent; expressed as osmol/kg; used to identify the number of moles of a particle per kilogram of water, not the kind of particle
Osmolality formula
mOSm/kg = 2(Na+ mmol/L) + (glucose mmol/L / 18) + (Urea N mmol/L / 2.8)
Osmol gap
Difference between the measured and calculated osmolality; measured Osm/kg - calculated Osm/kg
Colloid oncotic pressure (COP)
Pressure created in a solution by the presence of large proteins called colloids
Brain (B)-type natriuretic peptide (BNP)
Increases NaCl and H2O reabsorption; released in response to intravascular volume expansion and tends to reduce blood pressure and plasma volume