Chapter 12 Flashcards
cancer deaths per year:
More than 70,000
Most common cause of death in Canada:
cancer
how much percent cancer could be prevented through
changes in lifestyle ?
More than 60%
Tobacco use accounts for:
1/3 of all cancer deaths
Diet & exercise and their relationship to obesity
accounts for another:
30% of all deaths
abnormal, uncontrolled cellular growth:
cancer
cancerous and capable of
spreading; neoplasm:
Malignant tumour
non-cancerous and nonspreading:
Benign tumour
spread of cancer cells from one
part of the body to another:
Metastasis
metastasis spreads via:
Blood vessels
Lymphatic system
any substance that causes cancer:
Carcinogen
common cancers:
lung cancer Colon and Rectal Cancer Breast Cancer Prostate Cancer Skin Cancers Oral cancer Testicular cancer
Leading cause of cancer death:
lung cancer
lung cancer stats:
estimated that 177 800 Canadians would
be diagnosed with cancer with 75 000 deaths
Chief risk factor of lung cancer:
smoking
Symptoms of lung cancer=
persistent cough, chest pain
treatment of lung cancer:
combination of surgery, radiation,
chemotherapy
Survival rate of lung cancer=
15% after five years
Second leading cause of cancer death:
Colon and Rectal Cancer
Risk factors of colon and rectal cancer:
Age (e.g., 50 and older) Pre-existing polyps Heredity Inactivity and obesity Diets high in red meat, smoked foods, simple sugars Excessive alcohol consumption Smoking
Symptoms of colon and rectal cancer:
Bleeding from the rectum
Change in bowel habits
Testing for colon and rectal cancer:
Stool blood test
Sigmoidoscopy or colonoscopy
Treatment for colon and rectal cancer:
Surgery is primary method of treatment
Most common female cancer:
breast cancer (1 in 9 women)
Second to lung cancer in the number of cancer
deaths among women:
breast cancer
Causes/risk factors of breast cancer:
Heredity
Long-term exposure to high blood levels of estrogen
Early onset of menstruation
Late onset of menopause
No children or first child after age 30
Obesity
Current use of HRT (hormone replacement therapy)
estrogen levels increased by alcohol use
Inactivity
Diet low in vegetables and fibre
Early detection of breast cancer:
Mammography (low-dose X ray) after age 40
Clinical breast exams
Breast awareness and self-examinations
Diagnosis of breast cancer:
Ultrasonography = imaging method using high-pitched sound
Biopsy = removal and examination of a small piece of body tissue
Treatment of breast cancer:
Surgery (lumpectomy, mastectomy)
Chemotherapy or radiation, social support
Most common cancer in men and second to lung
cancer in the # of cancer deaths among men:
Prostate Cancer
Risk factors of prostate cancer:
Age (greater than 65) Heredity Lifestyle factors Diets high in calories, dairy products, and animal fat and low in plant foods Obesity and inactivity History of STIs
Detection and diagnosis of prostate cancer:
Rectal exam
PSA (prostate-specific antigen) blood test
Ultrasound
Biopsy
Treatment of prostate cancer:
Surgery
Radioactive seeds
Survival rate of prostate cancer =
nearly 100% at 5 years
Cancers of the Female Reproductive Tract:
Cervical cancer
Uterine or Endometrial Cancer
Ovarian cancer
Clear cell cancer of vagina or cervix
cervical cancer:
Linked to infection with HPV (genital warts)
Detected with the Pap test = scraping of cells from the
cervix for examination
Abnormal cells are monitored over time; if they progress
toward malignancy, they are removed
Uterine or Endometrial Cancer:
Risk factors similar to those for breast cancer
Usually detected by pelvic examination
Treatment = surgery, possibly combined with
radiation and chemotherapy
Ovarian cancer
Risk factors similar to breast and endometrial cancer
Anything that lowers the lifetime # of ovulation cycles reduces risk
Usually has no symptoms and is difficult to detect
Treatment = surgery
Survival rate is low due to late detection
Clear cell cancer of vagina or cervix is more common among
daughters of women who took:
DES (diethylstilbestrol) to
prevent miscarriage during pregnancy
Most common type of cancer, when cases of the
highly curable forms are included:
Skin Cancers
Primary risk factor of skin cancers:
exposure to ultraviolet (UV) radiation
damages connective tissue, leads to
premature aging of the skin, causes skin cancer:
UVA
causes sunburn, damages eyes and immune
system, causes skin cancer:
UVB
cancer of the
deepest layers of the skin:
Basal cell carcinoma
cancer of the
surface layers of the skin:
Squamous cell carcinoma
a malignant tumour of the
skin that arises from pigmented cells,
usually a mole; the most dangerous form
of skin cancer:
melanoma
ABCD Test for Melanoma:
A-asymmetry- is one half unlike the other?
B- Border irregularity
C- color variation
D- diameter larger than 1/4 inch
Preventing Skin Cancer:
Wear long-sleeved shirts, long pants, hats (cover skin)
Use a broad-spectrum sunscreen with a high SPF (30+)
Apply sunscreen 30 minutes before sun exposure, 15–30
minutes after exposure begins, and frequently after
that; apply extra if you are using insect repellant
containing DEET
Avoid sun exposure between 10 AM and 4 PM
Check UV index
Avoid tanning salons
Oral cancer
Key risk factors
tobacco use (including spit tobacco)
consumption of alcohol
oral cancer is:
Easy to detect but difficult to treat
Most frequent in men over 40
Rare overall (less than 1% cancers in men), but most common cancer in men age 20–35 years:
testicular cancer
testicular cancer Can be detected with
self-examination
Pancreatic cancer =
very deadly form of cancer
other cancers:
Bladder cancer Kidney cancer Brain cancer Leukemia Lymphoma
Leukemia =
cancer of white blood cells
Lymphoma =
cancer that begins in the lymph nodes
deoxyribonucleic acid, a chemical substance that
carries genetic information:
DNA
threadlike body in a cell nucleus that
contains molecules of DNA:
Chromosome
section of chromosome that contains the
instructions for making a particular protein:
gene
A mutated gene no longer contains:
the proper code for
producing its protein
gene involved in the transformation of a
normal cell into a cancer cell:
Oncogene
Cancer promoters=
compounds that accelerate cell growth
dietary factors of cancers:
too much: Dietary fat and meat Alcohol Fried Foods not enough: Fibre Fruits and vegetables Carotenoids Antioxidants - prevent free radicals from damaging DNA Phytochemicals
Limit consumption of:
charred, blackened, cured,
and smoked meat and fish
The Causes of Cancer:
Inactivity and obesity
Carcinogens in the environment
Carcinogens in the environment:
Ingested chemicals (e.g., food preservatives)
Environmental and industrial pollution
Radiation
Microbes (e.g., viruses, bacteria)
7 major warning signs of cancer:
Change in bowel or bladder habits A sore that does not heal Unusual bleeding or discharge Thickening or lump Indigestion or difficulty in swallowing Obvious change in a wart or mole Nagging cough or hoarseness