Chapter 12 Flashcards
Who tested on mice?
Griffith.
What did Griffith discover?
Griffith discovered that when a harmless bacteria strain was combined with a harmful heat-killed bacteria strain the harmless bacteria would become virulent. This is an example of transformation
What does virulent?
Virulent means able to cause disease.
What is transformation?
Transformation is when there is a change in a phenotype caused when bacterial cells take up foreign genetic material.
What did Avery discover?
Avery found that DNA is the material responsible for transformation.
What did Hershey and Chase discover?
Using bacteriophages Hershey and Chase discovered DNA, not proteins is the source of genetic material.
What is a bacteriophage?
Bacteriophages are viruses that infect bacteria
What is the shape of DNA?
A double helix of nucleotides
What does DNA do?
Controls the production of proteins.
What is a nucleotide?
The monomer of DNA.
What are a nucleotide’s three parts?
Five Carbon Sugar, A phosphate group, and one nitrogen base.
What are the four options of nitrogen base for a nucleotide?
Adenine, Guanine, Cytosine, or Thymine.
Who discovered the Laws of Base-Pairing?
Erwin Chargaff.
Which nitrogen bases pair together?
Adenine pairs to Thymine and Cytosine pairs to Guanine.
How are nitrogen bases paired?
Hydrogen bonds.
Who ‘discovered’ the double helix?
Watson and Crick.
Who actually discovered the double helix, but died because they were exposed to radiation?
Rosalind Franklin.
What does DNA look like?
A twisted ladder.
What are the ‘sides’ of the ‘ladders’ of DNA?
Alternating Sugar and Phosphate groups.