Chapter 11- The Musculoskeletal System Flashcards

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1
Q

3 types of muscle

A
  1. skeletal (supporting body/ voluntary movement)
  2. smooth (involuntary movement/ peristalsis)
  3. cardiac (maintain rhythmic contraction of heart w/o NS input)
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2
Q

sarcomeres

A

basic contractile unit of skeletal muscle. made of thick and thin filaments. thick are bundles of myosin. thin are made of actin (troponin and tropomyosin help regulate interaction b/w thin and thick)

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3
Q

different fibers in skeletal muscle

A
red fibers (aka. slow-twitch fibers)- high myoglobin content
white fibers (aka. fast-twitch fibers)- contain less myoglobin
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4
Q

smooth vs skeletal muscle nuclei

A

skeletal- multinucleated

smooth- single nucleus

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5
Q

tonus

A

constant state of low-level contraction by smooth muscle

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6
Q

myogenic activity

A

smooth muscle can contract without NS input. muscle cells contract directly in response to stretch or other stimuli. both smooth and cardiac exhibit myogenic activity.

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7
Q

cardiac muscle characteristics

A

autonomic NS. appears striated. may contain two nuclei, usually only one. each cell is connected by intercalated discs which contain gap junctions (cytoplasm is shared b/w those cells)

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8
Q

what is required for muscle contraction?

A

Ca2+ and ATP

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9
Q

I-band

A

only thin filaments

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10
Q

H-zone

A

only thick filaments

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11
Q

which band always remains constant with respect to size

A

A-band

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12
Q

which structure separates each sarcomere

A

Z-line

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13
Q

sarcoplasmic reticulum (SR)

A

cover myofibrils. modified endoplasmic reticulum with high Ca2+ concentration.

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14
Q

sarcolemma

A

cell membrane of myocyte. capable of propagating and distributing action potential.

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15
Q

myocyte

A

muscle cell

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16
Q

where does Acetylcholine bind during an action potential

A

receptors on the sarcolemma, causing depolarization

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17
Q

what is responsible for the powerstroke in muscle movement

A

the dissociation of ADP and P from myosin. the binding of ATP is required for releasing the myosin head from the actin filament.

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18
Q

without Ca2+…

A

myosin-binding sites will be covered by tropomyosin and contraction will be prevented

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19
Q

tetanus

A

very frequent contractions so that the muscle is unable to relax. this can cause muscle fatigue

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20
Q

creatine phosphate

A

created by transferring phosphate from ATP to creatine during times of rest (1 way to reserve energy b/c it can be reversed quickly to generate ATP quickly)

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21
Q

axial skeleton

A

skull, vertebral column, ribcage, hyoid bone (small bone in anterior of neck used for swallowing.

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22
Q

appendicular skeleton

A

bones of limbs, pectoral girdle, and pelvis

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23
Q

skeleton is created from 2 major components

A

bone and cartilage

24
Q

3 major segments of bone

A
  1. epiphysis (ends)
  2. metaphysis(near the end)
  3. diaphysis (middle long part)
25
Q

epiphysis

A

epiphyseal plate (growth plate, site of longitudinal growth), spongy bone, periosteum (muscle attachment here/ fibrous sheet that surrounds long bones)

26
Q

diaphysis

A

periosteum, compact bone, marrow cavity

27
Q

compact bone vs. spongy/cancellous bone

A

compact- strong and dense, outermost bone

s/c- lattice structure with trabeculae filled with bone marrow, internal core of bone

28
Q

bone marrow

A

red marrow- hematopoietic stem cells (generate all cells in blood)
yellow marrow- made of fat and is relatively inactive

29
Q

tendons

A

attach muscle to bone

30
Q

ligaments

A

pieces of fibrous tissue that connect bones together at joints. strengthen movable joints.

31
Q

bone matrix

A

organic (collagen, glycoproteins, peptides) and inorganic (Ca, phosphate, hydroxide ions all together form hydroxyapatite crystals) components

32
Q

osteons/ Haversian systems

A

structural units of bony matrix.

33
Q

lamellae

A

each osteon contains concentric circles of bony matrix.

34
Q

Haversian canals

A

longitudinal channels (those with axis parallel to the bone)

35
Q

Volkmann’s canals

A

transverse channels (those with an axis perpendicular to the bone)

36
Q

lacunae

A

between lamellar rings are these small spaces. these house mature bone cells known as osteocytes.

37
Q

canaliculi

A

lacunae are interconnected by tiny channels which allow for the exchange of nutrients and wastes between osteocytes and the Haversian and Volkmann’s canals

38
Q

osteoblast vs. osteoclast

A

blast- builds bone (uses Ca and phosphate from bone)

clast- chew bone, macrophages of bone and resorb it.

39
Q

parathyroid hormone

A

peptide hormone released by the parathyroid glands in response to low blood Ca, promotes resorption of bone, increasing the concentration of Ca and phosphate in the blood

40
Q

Vitamin D

A

activated by parathyroid hormone also promotes the resorption of bone.

41
Q

calcitonin

A

a peptide hormone released by the parafollicular cells of the thyroid in response to high blood calcium, promotes bone formation, lowering blood calcium levels

42
Q

cartilage

A

chondrin (secreted by cells called chondrocytes)- softer and more flexible than bone

43
Q

endochondral ossification

A

hardening of cartilage into bone. responsible for formation of most long bones in body.

44
Q

intramembranous ossification

A

undifferentiated embryonic connective tissue (mesenchymal tissue) is transformed into and replaced by bone— this occurs in the skull

45
Q

immovable joints

A

bones fused together to form sutures or similar fibrous joints (found in head, anchor bones of skull together)

46
Q

movable joints

A

joints (elbow/ knee), ball-and-socket joints (shoulder/ hip)

47
Q

what do ligaments consist of

A

synovial capsule (encloses actual joint cavity-articular cavity)

48
Q

synovium

A

layer of soft tissue that secretes synovial fluid (lubricates movement of structures in the joint space)

49
Q

articular cartilage

A

contributes to the joint by coating the articular surfaces of the bones so that impact is restricted to the lubricated joint cartilage

50
Q

synergistic

A

working together to accomplish the same function

51
Q

flexor and extensor

A

antagonistic pairs. flexor- decreases angle across joint. extensor- increases this angle.

52
Q

abductor

A

moves part of body away from midline

53
Q

adductor

A

moves part of body toward the midline

54
Q

medial vs. lateral rotation

A

m- rotating axis toward midline

l- rotating axis away from midline

55
Q

what causes Ca2+ release from bones

A

parathyroid