Chapter 11: Structural Disorders and Neoplasms of the Reproductive System Flashcards

1
Q

What is the typical alignment of the uterus?

A

slight anteversion – fundus points towards belly button

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2
Q

What are 5 types of disorders of uterus structure?

A
  1. retroversion: fundus of uterus points towards head or slightly back towards spine
    * occurs 2 months postpartum – should returnt o normal
    * 1/3 do not return – may make future conception more difficult
    * rarely symptomatic
  2. prolapse
    * mild or complete
    * complete – painful sex, urinary incontinence
  3. cystocele: protrusion of bladder into vagina
    * often accompanies uterine prolapse
    * feels like something is in vagina
    * issues with voiding or stooling – may have trouble emptying
  4. rectocele: herniation of rectal wall through vagina
    * needs to be repaired surgically
    * often accompanies uterine prolapse
    * feels like something is in vagina
  5. genital fistulas: perforations between organs and genital tract organs
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3
Q

What are ovarian cysts?

A
  • benign cysts that are often associated with menstrual cycle
  • asymptomatic unless ruptured –> severe abdominal pain
  • PCOS – endocrine imbalance due to multiple cysts on ovaries which results in high estrogen
  • dermoid cysts – comprised of hair and bone that develop in childhood
  • ovarian fibromas – comprised of connective tissue
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4
Q

What are uterine polyps?

A
  • endometrial or cervical in origin
  • benign polyps that rarely recur after removal
  • most common in multip women 40+
  • unknown etiology
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5
Q

What are leiomyomas?

A
  • AKA fibroid tumors, fibromas, myomas, fibromyomas
  • most common benign tumor
  • tumors arise from muscle tissue of uterus
  • rarely malignant
  • growth influenced by ovarian hormones
  • spontaneously shrink after menopause
  • mostly asymptomatic
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6
Q

How are leiomyomas managed?

A
  • medications – gonadotropin release hormone agonists (reduce size), NSAIDs
  • uterine artery embolization (UAE) – cuts off blood flow to fibroid
  • surgery – laser, myomectomy, hysterectomy
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7
Q

What are Bartholin cysts?

A
  • most common benign lesions of the vulva
  • obstruction of the Bartholin duct, causing it to enlarge
  • recurrence in women is common
  • treatment is marsupialization – formation of new duct for drainage (permanent opening)
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8
Q

What is vulvodynia?

A

vulvar pain

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9
Q

What is a major risk factor in development of malignant cancers of endometrium, cervix, ovaries, vulva, vagina, and uterine tubes?

A

obesity

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10
Q

What is endometrial cancer?

A
  • malignant cancer in the endometrial tissue
  • hormone imbalance is the most significant risk factor
  • s/s: abnormal uterine bleeding
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11
Q

What is ovarian cancer?

A
  • malignant cancer of the ovaries
  • definitive screenings do not exist – usually diagnosed in advance stage
  • s/s: vague, but abdominal bloating is one
  • white women of North American or Northern European descent and older women are at highest risk
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12
Q

What is cervical cancer?

A
  • malignant cancer of the cervix
  • 90% caused by HPV
  • most reliable method to detect preinvasive cancer = Pap smear
  • confirmation of cervical cancer = colposcopy and biopsy
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13
Q

What is vulvar cancer?

A
  • malignant cancer of vulva
  • slow growing, slow extending, and late to metastasize
  • most common site = labia majora
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14
Q

What is vaginal cancer?

A
  • malignant cancer of vagina
  • most at risk = women 70 - 90
  • most lesions are squamous cell carcinomas
  • may be caused by chronic vaginal irritation, vaginal trauma, and genital viruses
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15
Q

What is uterine tube cancer?

A
  • malignant cancer of uterine tubes
  • most at risk = women 50 - 60
  • unknown etiology
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16
Q

How likely is cancer to occur during pregnancy?

A

relatively infrequently – 1 out of 100 women

17
Q

What are the types of cancer that may occur during pregnancy?

7 types

A
  1. breast cancer
  2. cervical cancer
  3. leukemia – cancer of blood forming tissues
  4. Hodgkin disease/lymphoma – WBCs grow uncontrollably, causing swelling of lymph nodes
  5. melanoma
  6. thyroid cancer
  7. colon cancer
18
Q

If a woman is on cancer treatments but wants to get pregnant, what is the recommended timeline for her to conceive?

A

wait at least 2 years after the end of therapy before conceiving

19
Q

What is gestational trophoblastic disease (GTD)?

A
  • malignant tumors that develop during abnormal pregnancies
  • most curable gynecologic malignancy
  • follow HcG (human chorionic gonadotropin) hormones for at least 1 year