Chapter 11 Flashcards
What makes Eukaryotic cell Reproductive signals different from prokaryotic ones?
1.Eukaryotic cells do not constantly divide whenever condition are adequate. 2. need to benefit entire organism 3. Some cells become specialized and no longer divide
Cytokinesis
division of cytoplasm and cell separation
Sister Chromatids
newly replicated chromosomes closely associated with each other
Mitosis
process that segregates newly replicated chromosomes into two new nuclei
Cell Cycle
period from one cell division to the next
3 Broad stages of the cell cycle
Interphase, Mitosis, Cytokinesis
Interphase
Nucleus is visible, typical cell functions occur
G1 Phase
between cytokinesis and S phase, cell prepares to replicate
S Phase
DNA is replicated, sister chromatids remain together
G0 Phase
Inactive resting phase, cell enters if not preparing for division
Restriction point (G1-S phase transition)
commitment to DNA replication and subsequent cell division
G2 phase:
Cell prepares for Mitosis
What are the phases of interphase
G1, S, and G2
Photophosyrlation
addition of a phosphate group
Kinase
Enzyme that catalyzes transfer of a phosphate group from ATP to a target protein
Cyclin-Dependent Kinases (CDKs)
control progress through the cell cycle
Cyclin
allosterically regulates CDKs
How does Cyclin regulate CDK’s?
by binding to CDK, and exposing it’s active site, turning it on
Cell Cycle checkpoints
regulate progress through the cell cycle by checking to see if everything is in order
G1 Checkpoint Trigger
DNA damage
S Checkpoint trigger
incomplete DNA replication or DNA damage
G2 Checkpoint trigger
DNA damage
M Checkpoint trigger
chromosomes unattached to spindle
RB protein
inhibits the cell cycle, unless it is phosphorylated by cyclin-CDK, in which case it no longer blocks the cell
Growth Factors
proteins that allow for cell division
Nucleosomes
Histones
proteins with positive charges that attract negative phosphate groups of DNA and pack them
Nucleosomes
beadlike units formed by the interaction of histones and DNA, 10:1 compaction
Chromatin
DNA molecules bound to proteins, 50:1 compaction
Cohesins
proteins that hold sister chromatids together during G2
Centromere
attachment site of sister chromatids, as well as spindle fibers