Chapter 10 Spermatogenesis

Question 1

LH last 10-20 minutes 4-8 times per day and targets?

Answer 1

Lyedig cells

Question 2

FSH occurs in lower concentrations because of inhibin secretion and longer half life but last longer periods. what does FSH target?

Answer 2

Sertoli cells

Question 3

The leydig cells in males are similar to what in the female?

Answer 3

Theca interna cells of the antral follicles in the ovary

Question 4

What is the overall goal of spermatogenesis?

Answer 4

Produce sperm

Question 5

Male GnRH secretion occurs in intermittent, and frequent pulses lasting a few minutes which causes?

Answer 5

FSH and LH

Question 6

What do Sertoli cells secrete?

Answer 6

inhibin and DHT inhibin (inhibits FSH)

Question 7

T or F. Leydig cells contain membrane bound receptors of LH

Answer 7

True

Question 8

T or F. Leydig cells synthesize testosterone upon binding of LH.

Answer 8

False, Progesterone. Progesterone is then converted to testosterone

Question 9

T of F. Secretion of testosterone from leydig cells is pulsatile

Answer 9

True

Question 10

What function is a pulsatile release of LH necessary to maintain?

Answer 10

proper testicular function

Question 11

What happens to LH receptors when there is too much release of LH?

Answer 11

become unresponsive

Question 12

What happens when LH receptors become unresponsive?

Answer 12

low levels of testosterone production

Question 13

What are the goals of speratogenesis?

Answer 13

1. provide a continuous supply of gametes

2. …

Question 14

Define Spermatogenesis.

Answer 14

all cell divisions and all morphologic changes that take place within the semineiferous epithelium

Question 15

Where does spermatogenesis take place?

Answer 15

seminiferous tubles

Question 16

What changes the developing germ cell?

Answer 16

cell division and morphological changes

Question 17

What are the 3 phases?

Answer 17

1. proliferation phase
2. meiotic phase
3. Differentiation phase

Question 18

T or F. developing germ cells are never connected by intercellular bridges

Answer 18

False, all stages are connected by intercellular bridges so the cytoplasm is interconnected

Question 19

What does the proliferative phase consists of what kind of division?

Answer 19

mitotic divisions of diploid spermatogonia

Question 20

Where is prorliferative mitotic division take place?

Answer 20

periphery of a seminiferous tubule near the basement membrane and then move to the lumen as they proliferate

Question 21

Several A- spermatogonia generations go through mitotic divisions to create?

Answer 21

I and then B- spermatogonia

Question 22

What are the different spermatogonia phases?

Answer 22

A1, A2, A3, A4, I, B

Question 23

What is an important part of the proliferative phase?

Answer 23

renewal

Question 24

What is renewal?

Answer 24

the ability for some spermatogonia to revert to stem cells allowing those stem cells to later redevelop into spermatogonia
Stem cells are maintained to ensure continuous spermatogenesis

Question 25

How many spermatids can one A- spermatogoia produce?

Answer 25

256 spermatids