Chapter 10 (Muscle Tissue) Flashcards

1
Q

Muscle FIbers are bundled within a

A

fascicle

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2
Q

There are ___ layers of skeletal muscle C.T. wrappings, they are___

A

3
1)Epimysium (Outermost layer… Dense Ireg.)
2)Perimysium(white spidering structure Dense Ireg.)
3)Endomysium (Inner most…Areolar)

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3
Q

There are ___ types of fascia, they are ___

A

two

1)Deep (separates individual muscles)
2) Superficial (Separates muscle From skin)

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4
Q

Skeletal is ___ and has extensive ___

A

vascularized
blood vessels

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5
Q

A muscle cell consists of ___ parts, they are ___

A

3
1) Sarcoplasm (cytoplasm)
2) Multiple nuclei
3) Sarcolemma (plasma membrane)

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6
Q

Muscle fibers are __ cell

A

one

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7
Q

Sodium which is __ charged, is the main excitatory ion.

A

positively

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8
Q

Potassium ___ down and restores the _____

A

resting membrane potential

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9
Q

The Terminal cisternae holds onto ___

A

calcium

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10
Q

Calcium binds to ___(2)

A

calmodulin
Calsequestrin

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11
Q

the pneumonic device for terminal cisternae is ___

A

treasure chest

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12
Q

Myoglib (which is a protein) holds ____

A

extra oxygen in muscle cells

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13
Q

When a motor neuron fires there is the _____ principle (everything or nothing has to contract)

A

all or none

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14
Q

A.C.H. diffused across cleft, binds to receptors, excites Fiber

A

ok

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15
Q

When thinking about muscles… the configeration of them goes ___(5)

A

1)Terminal Cisterae (holds calcium)
2)cytosol
3)T-tubule (voltage sensitive…green main tube that carries charge
4)Cytosol
5)Terminal Cistertae

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16
Q

Myofilaments are __ proteins. There are two types which are ___

A

1)contractile
2)thick (Myosin….which has myosin heads)
3)thin (twisted strand of actin that has an myosin binding site)

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17
Q

What are the two regulatory proteins in thin filaments ___

A

1) tropomyosin
2) troponin

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18
Q

Myofilaments are arranged in repeating units called __. They are delineated at both ends by ___

A

sarcomeres
Z discs

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19
Q

Sarcomere runs from ____ to ____. The ___ is the length of the thick filament. The ____ is on either side of the A band.

A

z disc
A band (thick filaments)
I band (only contains thin filament)

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20
Q

The ___ is the central portion of the A band

A

H zone

21
Q

The ___ is the middle of the H zone

A

M line

22
Q

__ stabilized the thick filaments

A

Connection (green spiral)

23
Q

A ___ controls muscle fibers

A

motor unit

24
Q

Small motor units allow for ___

A

precise control of force output

25
Q

The gates that release calcium are voltage ____

A

sensitive

26
Q

progression of neuromuscular junction

A

1) neuron excites muscle fiber by sending a nerve signal down and propagating calcium into the synaptic knob
2) calcium-binding causes vesicles to merge with the plasma membrane and ACh is exocytosed into synaptic cleft
4) ACH diffuses across the synaptic cleft to bind with ACh receptors.

27
Q

The sarcolemma of an unstimulated skelatal muscle fiber a a RMP of ___

A

-90mv

28
Q

Depolarization occurs as the ___

A

voltage-gated NA+ channels open and sodium enters

29
Q

Repolarization occurs when the voltage-gated sodium channels close and sodium ____

A

moves out of the cell

30
Q

tetanus is caused by the toxin

A

clostridium tetani (blocks the release of inhibitory neurotransmitter)

31
Q

Botulism is caused by

A

clostridium botulinum (prevents the release of ACh at synaptic knobs

32
Q

3 ways to create ATP

A

1) creatine phosphate
2) Glycolysis
3) Aerobic cellular respiration

33
Q

When there is low oxygen available lactate forms from __

A

pyruvate (this is called lactate dehydrogenase)

34
Q

Oxidative fibers that are fatigue-resistand are

A

red

35
Q

glycolytic fibers which are fatigable are

A

white fibers

36
Q

the three types of skeletal fibers are

A

1)slow oxidative
2) fast oxidative
3) fast glycolytic

37
Q
A

ok

38
Q

Recruitment is also called

A

multiple motor unit summation

39
Q
A

ok

40
Q

Isometric contraction

A

tension is increased by insuffcient to overcome resistance (baby)

41
Q

Isotonic contraction

A

overcomes resistance

42
Q

The tension a mucle produces depends on

A

the length at time of stimulation

43
Q

Hypertrophy is when

A

muscle increases in size

44
Q

atrophy is when

A

muscles decrease in size due to lack of use

45
Q

calmodulin is a

A

protein that binds calcium to trigger contraction

46
Q

myosin light-chain kinase (MLCK):

A

enzyme that phosphorylates myosin heads
when activated by calmodulin

47
Q

myosin light-chain phosphatase

A

enzyme that dephosphorylates myosin head
(required for relaxation)

48
Q

Myogenic response

A

is contraction in reaction to stretch

49
Q

Stress-relaxation response

A

is relaxation after prolonged stretch