Chapter 10 - Mitosis Flashcards

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1
Q

Cytogenetic

A

The field of genetics involving microscopic examination of chromosomes and cell division

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2
Q

Purpose of cytogenic

A

To better understand the structure and behavior of the DNA during cell divisions

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3
Q

Diploid

A

Two sets of chromosomes

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4
Q

Somatic cells

A

All are diploid

Any cells that are not involved in sexual reproduction

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5
Q

Haploid

A

Only one set of chromosomes
All sex cells are haploids
Sex cells are the sperm and egg cells

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6
Q

Three phases of interphase

A
  1. G1
  2. S
  3. G2
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7
Q

G1

A

Cell grows
Sometimes a cell enters G0 instead of the next phase
A cell in G0 will not divide

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8
Q

S

A

DNA replicates and produces sister chromatids

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9
Q

G2

A

Cell grows and gets prepared for the next phase

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10
Q

Sister chromatids

A

Two identical copies that stay joined to each other.

Tightly joined at the “waist” called the centromere.

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11
Q

Centromere

A

Serves as an attachment site for the kinetochore used in sorting chromosomes.

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12
Q

Mitosis

A

Purpose is to separate sister chromatids so that each daughter cell gets an equal number of chromosomes.
If the parent cell has 20 chromosomes, each daughter cell has 20 chromosomes.

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13
Q

Prophase

A

Spindle fibers form

Chromatin becomes condensed

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14
Q
  1. Prometaphase
A

Spindle fibers interact with sister chromatids.

Two kinetochores on each pair of sister chromatids are attached to kinetechore microtubules from opposite poles.

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15
Q
  1. Metaphase
A

Spindle fibers attached to the kinetechores at the centromeres move the sister chromatids to the middle of the cell.
Sister chromatids are lined up at the imaginary line called the metaphase plate.

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16
Q
  1. Anaphase
A

Kinetochore microtubules shorten, pulling sister chromatids apart toward the pole to which they are attached.

17
Q
  1. Telophase
A

Nuclear envelopes form around the two clusters of chromosomes.

18
Q

Cytokinesis

A

Two nuclei are segregated into separate daughter cells.
Animal cells- a cleavage furrow constructs like a drawstring to separate the cells.
Plant cells- a cell plate forms a wall between the two daughter cells

19
Q

Cyclins and cyclin-dependent kinases (cdks)

A

Cyclins are proteins that bind to the enzymatic cdks.
Purpose of cyclins and cdks is to let the cell know it is ready to move on to the next phase.
During G1, G1 cyclins bind to G1 cdks when the cell is ready to go through DNA replication.
During S, S cyclins bind to S cdks when DNA replication is completed and the cell is ready to go on to G2. Each phase of cell cycle has their own cyclins and cdks.

20
Q

Cancer

A

Uncontrolled cell division.
If the tumor does not spread to surrounding tissue, then the tumor is a benign tumor (non-cancerous).
If the tumor invades the surrounding tissue, then the tumor is a malignant tumor (cancerous).
If cancer cells break free from the tumor and become mobile, then the cancer has metastasized.

21
Q

Prokaryotic cell division

A

Called binary fission, or splitting into two parts.