Chapter 10: Autonomic and Somatic Nervous System Flashcards

1
Q

What does the ANS innervate

A

The autonomic nervous system innervates smooth muscle, cardiac muscle and glands (often referred to as visceral effectors) because they are associated with the internal organs of the body

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2
Q

what type of control does ANS operate under

A

without unconscious control by either increasing (exciting) or decreasing (inhibiting) ongoing activities in their effectors

Autonomic = autonomous, without control of the CNS

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3
Q

dual innervation

A

an organ or tissue is controlled by both divisions of the autonomic nervous system: the sympathetic and parasympathetic systems

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4
Q

parasympathetic nervous system

A
  • Enhances rest and digest activities, which conserve and restore body energy during times of rest and recovery
  • Also known as the craniosacral division of the ANS
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5
Q

What does “craniosacral” mean?

A

Cranio” = comes from the brainstem (cranial nerves III, VII, IX, X)

“Sacral” = comes from the sacral region of the spinal cord (S2–S4)

  • restore rest and restorable body functions
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6
Q

sympathetic nervous system

A

Produces the fight or flight response which prepares the body for emergency situations

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7
Q

What are the two main divisions of the ANS and their functions?

A

Parasympathetic (craniosacral): Rest and digest—conserves energy

Sympathetic (thoracolumbar): Fight or flight—prepares body for stress

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8
Q

What is the enteric nervous system (ENS)?

A

A third branch of the ANS that independently controls the GI tract, with its own sensory, motor, and interneurons

  • involuntary
  • contains sensory neurons, interneurons and motor neurons
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9
Q

How does the autonomic nervous system usually operate?

A

Without conscious control, increasing (exciting) or decreasing (inhibiting) ongoing activities in their effectors

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10
Q

What are the two main branches of the autonomic nervous system?

A
  • Parasympathetic nervous system
  • Sympathetic nervous system
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11
Q

What is the primary function of the parasympathetic nervous system?

A

Enhances rest and digest activities, conserving and restoring body energy during rest and recovery

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12
Q

What is the main function of the sympathetic nervous system?

A

Produces the fight or flight response, preparing the body for emergency situations

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13
Q

What is the role of sensory neurons in the enteric nervous system?

A

Monitor chemical changes and stretching within the GI tract

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14
Q

What are the two types of autonomic motor pathways?

A
  • Preganglionic neuron
  • Postganglionic neuron
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15
Q

Where does the first neuron, the preganglionic neuron, originate?

A

In the brain or spinal cord

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16
Q

describe the autonomic motor pathway

A

prganglionic neuron (CNS) –> autonomic ganglion (PNS) –> postganglionic neuron –> visceral effector

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17
Q

What is a ganglion?

A

A cluster of neuronal cell bodies in the PNS

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18
Q

What characterizes the postganglionic neuron?

A

Lies entirely in the PNS and relays action potentials from autonomic ganglia to visceral effectors

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19
Q

Where do parasympathetic and sympathetic neurons originate?

A

Parasympathetic: Brainstem & S2–S4 spinal cord

Sympathetic: T1–L2 spinal cord

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20
Q

Where are their ganglia located?

A

Parasympathetic: Near or in target organs (terminal ganglia)

Sympathetic: Near spinal cord (sympathetic trunk/collateral ganglia)

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21
Q

What is the role of chromaffin cells in the adrenal medulla?

A

They are modified sympathetic neurons that release epinephrine (80%), norepinephrine (20%), and dopamine into the blood

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22
Q

What is a cholinergic neuron and what receptors does it act on?

A

A neuron that releases ACh, acting on nicotinic (ganglia/skeletal muscle) and muscarinic (effectors) receptors

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23
Q

What are nicotinic acetylcholine receptors?

A

Receptors present in the plasma membrane of parasympathetic & sympathetic postganglionic neurons

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24
Q

What enzymes break down neurotransmitters in the ANS?

A

Acetylcholinesterase (AChE) breaks down ACh

Monoamine oxidase (MAO) inactivates NE

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25
What is an adrenergic neuron?
A neuron that releases norepinephrine (NE); acts on alpha (α) and beta (β) adrenergic receptors
26
What are the two main types of adrenergic receptors?
* Alpha receptors * Beta receptors
27
What is the function of chromaffin cells?
Produce and release catecholamines such as epinephrine and norepinephrine
28
What is autonomic tone?
The balance between sympathetic and parasympathetic activity, regulated by the hypothalamus
29
What does SLUDD stand for in parasympathetic responses?
used for effects: * S → salvation * L → lacrimation * U → urination * D → digestion * D → defecation
30
What are the three decreases associated with parasympathetic responses?
1) Decreased heart rate 2) Decreased diameter of bronchial tubes 3) Decreased diameter of pupils
31
What are "E" situations and sympathetic responses?
Exercise, Emergency, Excitement, Embarrassment → Fight or flight: ↑HR, ↑BP, bronchodilation, ↑glucose, pupil dilation
32
Why are the effects of sympathetic stimulation longer lasting?
1. Widespread axon divergence 2. ACh quickly inactivated; NE lasts longer 3. Epinephrine/NE from adrenal medulla prolong effect
33
What are autonomic reflexes?
Fast, involuntary responses occurring when action potentials pass through an autonomic reflex arc
34
Q18: What are the components of an autonomic reflex arc?
1. Sensory receptor 2. Sensory neuron 3. Integrating center (CNS) 4. Motor neurons (pre & postganglionic) 5. Effector (smooth muscle, cardiac muscle, glands)
35
Which structures receive only sympathetic innervation?
* Sweat glands * Aerector pili muscles * Kidneys * Spleen * Most blood vessels
36
What is the major control and integration center of the ANS?
Hypothalamus
37
What does the somatic nervous system control?
Voluntary movement of skeletal muscles
38
What is the neuromuscular junction (NMJ)?
is the synapse (connection) between a motor neuron and a skeletal muscle fiber. where a nerve signal is converted into a muscle contraction.
39
What are the steps of signal transmission at the NMJ?
1. AP arrives at end bulb 2. Ca²⁺ enters 3. ACh is released 4. ACh binds to nicotinic receptors 5. Na⁺ enters → End plate potential (EPP) 6. EPP → muscle AP → contraction 7. ACh broken down by AChE
40
What is the effect of ACh at the NMJ?
Causes skeletal muscle fiber to contract
41
What can alter events at the NMJ?
* Botulinum toxin * A-latroxin * Curare * Organophosphates
42
What is the role of motor neurons in the autonomic nervous system?
Propagate action potentials from the CNS to effectors
43
What is the main difference between the autonomic and somatic nervous systems?
The autonomic nervous system operates involuntarily, while the somatic nervous system operates voluntarily
44
What are the two types of autonomic motor neurons in the autonomic motor pathways?
Pre-ganglionic neuron and postganglionic neuron
45
Where does the pre-ganglionic neuron extend from and to?
From the CNS to an autonomic ganglion
46
What is the function of the postganglionic neuron?
Extends from the autonomic ganglion to the visceral effector
47
What are terminal ganglia associated with?
Parasympathetic nervous system
48
What are the two types of autonomic ganglia in the sympathetic nervous system?
* Sympathetic trunk * Collateral ganglia
49
What do chromaffin cells in the adrenal medulla release?
Epinephrine and norepinephrine
50
What are varicosities?
Varicosities = swollen areas along autonomic axons Function: Release neurotransmitters diffusely Found in: Smooth & cardiac muscle, glands Common in: Autonomic nervous system (especially sympathetic)
51
What triggers the exocytosis of synaptic vesicles at a varicosity?
An action potential reaching the varicosity
52
What type of responses can ACh and NE cause in the visceral effectors?
Excitatory or inhibitory responses
53
Give examples of excitatory responses in the ANS.
* Contraction of smooth muscle * Increased rate and force of contraction of cardiac muscle * Increased secretions of glands
54
Give examples of inhibitory responses in the ANS.
* Relaxation of smooth muscle * Decreased rate and force of contraction of cardiac muscle * Decreased secretions of glands
55
What does the parasympathetic nervous system regulate?
Activities that conserve and restore body energy
56
What does the sympathetic nervous system favor?
Body functions that support vigorous physical activity and rapid production of ATP
57
What does the somatic nervous system innervate?
Skeletal muscles of the body
58
What does a somatic motor pathway consist of?
A single somatic motor neuron extending from the CNS to the skeletal muscle
59
What neurotransmitter is released by somatic motor neurons?
Acetylcholine (ACh)
60
What is the effect of ACh at the neuromuscular junction?
Always excitatory, causing contraction of skeletal muscle
61
What happens when an action potential reaches the synaptic end bulbs of a somatic motor neuron?
Triggers exocytosis of synaptic vesicles, releasing ACh
62
What can alter events at the neuromuscular junction?
Botulinum toxin: blocks ACh release α-latrotoxin: overstimulates release Curare: blocks ACh receptors Organophosphates: block AChE, causing overstimulation → paralysis