Chapter 10 Flashcards
OPIATES
native to the Middle East
come from a poppy seed plant
AKA heroin-> very addictive drug
MEDICAL USES
Egyptians
Greek & Romans
9TH CENTURY
spread to India & China
where we start seeing it smoked
DISCOVERY OF MORPHINE
in 1803
major active form of opium
10x more potent than opium
WAR BETWEEN CHINA & GREAT BRITAIN
GB was giving China opium that they didn’t want
there was a war and GB won the port in Hon Kong
SOLDIERS DISEASE
many soldiers when they cam back from war were addicted to morphine because it cut out all the pain
HARRISON ACT
- didn’t allow opiates to be prescribed unless they were decreasing over time
- couldn’t be prescribed to known addicts
- heroin cold not be prescribed at all
UNCUT HEROIN
odorless powder
snorted
CHASING THE DRAGON
when the heroin was smoked
LOW QUALITY HEROIN
dark brown, has to be melted down to inject
DEATH RATE
50% - 100% times higher the death rate of the general population
at a higher risk for other diseases
25% of AIDS cases from sharing needles
DESIGNER HEROIN
made by chemist illegally
MPTP -> cause Parkinson’s
HISTORY ON OPIATES
men are more likely to use heroin
women are more likely to use prescription opiates
MAJOR DIFFERENCE IN HEROIN & MORPHINE
heroin is lipid soluble
easier to pass the blood brain barrier
once in the brain, heroin will turn into morphine
NALOXONE
opiate antagonist
given when someone has overdosed on heroin
can be mixed with Oxycontin to enhance pain relief