Chapter 1: Historical Overview Flashcards
Barbara McClintock & Harriet Creighton
demoed chromosomes recombine to create new genetic variations (in corn maize)
demoed DNA replication=semiconservative
meselson & stahl
4 qualities of living cells
- grow 2. reproduce 3. process information 4. respond to environment
meselson & stahl
demoed DNA replication=semiconservative
beadle & tatum
developed “one gene-one enzyme” hypothesis
sydney brenner & francois jacob
discovered DNA –> RNA (mRNA) –> directs production of proteins (polypeptides)
4 qualities of living cells
- grow 2. reproduce 3. process information 4. respond to environment
produced pic of molecular structure of DNA w/ x-ray crystallography
DNA composed of 2 antiparallel sugar-phosphate backbones w/ nitrogenous bases paired in interior
paired in specific combos: adenine w/ thymine, cytosine w/ guanine
maurice wilkins & rosalind franklin
franklin (x2)
molecular biology
study of gene structure and function at molecular level
- grow 2. reproduce 3. process information 4. respond to environment
4 qualities of living cells
discovered DNA
friedrich miescher
Archibald Garrod
suggestsed genes dictate phenotypes through enzymes
frederick griffith
found that DNA could be exchanged between bacteria –> changed genotype & phenotype (transformation)
demoed that chromosomes carry genes w/ fruit flies
discovered “linked genes”, sex-linked genes, and recombinance
thomas hunt morgan (x2)
particle of inheritance
gene