Chapter 1- Epidermis- Granular Layer Flashcards

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1
Q

The stratum granulosum is thicker in the nonhaired skin or the haired skin?

A

Nonhaired skin

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2
Q

Granular layer is variably present in haired or nonhaired skin?

A

haired skin

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3
Q

How thick is the granular layer in haired skin? non haired skin?

A

1-2 cells; 4 to 8 cells

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4
Q

What is the shape of cells in the granular layer? color?

A

flattened; basophilic

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5
Q

Describe the nuclei in the cells of the granular layer

A

shrunken nuclei

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6
Q

Describe the size and color of the keratohyalin granules in the cytoplasm of granular layer cells

A

deeply basophilic, large

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7
Q

In what layer are keratohyalin granules synthesized? Are these true granules- why or why not?

A

stratum granulosum; no; they lack a membrane- more accurately describes as insoluble aggregates

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8
Q

Keratohyalin graunles are composed of what three structures?

A

profilaggrin; keratine filaments; loricin

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9
Q

Filaggrin degradation products are important for what purpses?

A

normal stratum corneum hydration; filtering UV radiation

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