Chapter 1: Biochem and the organization of cells Flashcards

1
Q

Organism can be studied using the methods of chemistry and physics as all living things use:

A
  • The same types of Biomolecules
  • Energy
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2
Q

Biochemistry is a ___________________ in nature

A

Multidisciplinary

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3
Q

it combines biology and chemistry

A

Biochemistry

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4
Q

Uses results from many sciences to answer questions about the molecular nature of life processes.

A

Biochemistry

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5
Q

Simple molecules must have arisen from atoms:
Chemical Names

H2O -
CH4 -
CO2 -
NH3 -
N2 -
H2 -

A

Water
Methane
Carbon Dioxide
Ammonia
Nitrogen
Hydrogen gas

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6
Q

Study of compounds of carbon and hydrogen and their derivatives

A

Organic Chemistry

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7
Q

Biomolecules are part of the subject matter of organic chemistry because cellular apparatus of living organisms is made up of _________________ compounds.

A

Carbon

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8
Q

_____________ experiment in 1828

Ammonium Cyanate ——-> Urea

A

Friedrich Wöhler’s

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9
Q

Structure - Central carbon atom is bonded to a carboxyl group, an amino group, a hydrogen, and the R group

A

Amino acid

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10
Q
  • Compounds made up of carbon, hydrogen, and oxygen
  • General formula - (CH2O)n, where n is at least 3
  • Simplest form - Monosaccharides, or sugars
A

Carbohydrates

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11
Q

the most common monosaccharide

A

Glucose

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12
Q
  • Basic unit of the hereditary materials DNA and RNA
  • Composed of a five-carbon sugar, a nitrogencontaining ring, and one or more phosphate groups
A

Nucleotides

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13
Q

Form the molecular currency of the cell

A

Adenosine Triphosphate

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14
Q

Poorly soluble in water because they are composed of
long chains of hydrocarbons

Give an example of a simple lipid:

A

Lipids

Palmitic Acid

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15
Q

vital importance in biochemistry

A

Esters and anhydrides of phosphoric acid

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16
Q
  • Energy currency of the cell
  • Also containes ester and anhydrides linkages involving phosphoric acid
A

Adenosines Triphospate (ATP)

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17
Q

BIG BANG THEORY: ORIGIN OF THE UNIVERSE

Primordial fireball started to expand with great force as a result of an explosion
- Temperature was approximately_______________?

A

15 X 10^9 K

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18
Q

BIG BANG THEORY: ORIGIN OF THE UNIVERSE

____________ were the only elements present in the earliest stages of the Universe**

A

H, He and Li
(Hydrogen, Helium, Lithium)

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19
Q

Biomolecules

Gases present in the atmosphere of the early Earth

A

NH3, H2S, CO, CO2, CH4, N2, H2, and H2O
( Ammonia, Hydrogen sulfide, Carbon monoxide, Carbon Dioxide, Methane, Nitrogen, Hydrogen Gas, Water)

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20
Q

BIOMOLECULES

Experiments have demonstrated that important
biomolecules, such as proteins and nucleic acids,
could have arisen under ____________ conditions

A

Abiotic (nonliving)

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21
Q

Living cells include very large molecules, such as
proteins, nucleic acids, polysaccharides, and lipids

A

Biomolecules

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22
Q

Small molecules that may bond to many
others to form a polymer

A

Monomers

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23
Q

Greek - Mono + meros

__________ + ______ = Monomers

A

Single + Part

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24
Q

Biomolecules

Amino Acids →

A

Proteins

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25
# Biomolecules Nucleotides → __________
Nucleic Acids
26
# Biomolecules Monosaccharides → ___________
Polysaccharides
27
# Biomolecules Glycerol and 3 fatty acids → ___________
Lipids
28
# Biomolecules Macromolecules formed by the bonding of smaller units
Polymers
29
# Biomolecules Macromolecules formed by the **polymerization of amino acids**
Proteins
30
# Biomolecules Macromolecules formed by the **polymerization of nucleotides**
Nucleic acids
31
# Biomolecules Class of proteins that display catalytics activity
Enzymes
32
# Biomolecules Ability to **increase** the rate of a chemical reaction.
Catalytic Activity
33
Catalytic effectiveness of a given enzyme depends on its ____ sequence
Amino acid sequence
34
Relationship between the nucleotide sequence in nucleic acids and the amino acid sequence in proteins
Genetic Code
35
Serves as the coding material
Deoxyribonucleic Acid (DNA)
36
# Molecules to Cells - It has the capability to catalyzes itw own processing. - Considered to have been the original coding material and still serves this function in some viruses.
Ribonucleic Acid
37
# Molecules to Cells Appearance of a form of RNA capable of coding for its own replication was the pivotal point in the origin of life.
RNA World Theory
38
Original ____ both encoded and catalyzed its own replication
RNA
39
____ became the primary genetic material, and ____ took on only an intermediary role in the** synthesis of proteins**
DNA RNA
40
# Molecules to Cells ________ that seperates cells from their environment is a key point in the development of living cells.
Formation of Membranes
41
# Molecules to Cells Development of catalysis and the development of a coding system came about separately. - Combination of the two later in time produced life
Double-Origin Theory
42
- Microorganism that **lack** a distinct **nucleus** and membrane-enclosed organelles - * Include **bacteria** and **cyanobacteria**
Prokaryotes
43
- Organisms whose cells **have** a well-defined **nucleus** and membrane-enclosed organelles -
Eukaryotes
44
# Prokaryotes and Eukaryotes Yeasts and Paramecium
Unicellular
45
# Prokaryotes and Eukaryotes Animals and Plants
Multicellular
46
Membrane-enclosed portion of a cell with a specific function
Organelles
47
# Summary of Organelles and Their Functions Location of main genome; site of most DNA and RNA synthesis
Nucleus
48
# Summary of Organelles and Their Functions Site of energy-yielding oxidation reactions; has its own DNA
Mitochondrion
49
Site of photosynthesis in green plants and algae; has its own DNA
Chloroplasts
50
# Summary of Organelles and Their Functions Continuous membrane throughout the cell; rough part studded with ribosomes *(the site of protein synthesis)*
Endoplasmic Reticulum
51
# Summary of Organelles and Their Functions Series of flatted membranes involved in secretion of proteins from cells and in reactions that link sugars to other celluilar components.
Golgi Apparatus
52
# Summary of Organelles and Their Functions Membrane-enclosed sacs containing hydrolytic enzymes
Lysosomes
53
# Summary of Organelles and Their Functions Sacs that contain enzymes involved in the metabolism of hydrogen peroxide
Peroxisomes
54
# Summary of Organelles and Their Functions Separates the cell contents from the outside world; contents include organelles *(held in place by the cytoskeleton)* and the *cytosol*
Cell Membrane
55
# Summary of Organelles and Their Functions Rigid exterior layer of plant cells
Cell Wall
56
# Summary of Organelles and Their Functions Membrane-enclosed sac (plant cells)
Central Vacuole
57
# Classifying Living Organisms: Five-Kingdom System * Takes into account the differences **between prokaryotes and eukaryotes** * Provides classifications for ________ that are neither plants nor animals
eukaryotes
58
# Classifying Living Organisms: Five-Kingdom System Kingdoms:
* Monera * Protista * Fungi * Plantae * Animalia
59
# Source of Energy in Life Processes Ultimate source of energy for all life on Earth
Sun
60
# Source of Energy in Life Processes ____________organisms use light energy to drive the energy-**requiring synthesis of carbohydrates.**
Photosynthetic
61
# Source of Energy in Life Processes organisms consume carbohydrates and use them as energy sources
Nonphotosynthetic
62
Study of transformations and transfer of energy
Thermodynamics
63
Change in energy depends only on the state of the molecules present at the start of the process and the state of those present at the end of the process
Thermodynamics
64
Energetics of a chemical reaction If the change in free energy is ____________ (free energy **decreases**), the reaction is **spontaneous**
negative
65
Energetics of a chemical reaction If the change is ________ (free energy **increases**), the **reaction will not** occur unless energy is supplied from an **external source**
positive
66
can take several forms and can be converted from one form to another
Energy
67
Characteristic of a reaction or process that takes place without outside intervention
Spontaneous
68
* Diagnostic for the spontaneity of a reaction at constant temperature * Indicated by the symbol G
69
Sign of the change in free energy, ∆G, indicates the direction of the reaction * ________ - Spontaneous exergonic *** Exergonic**: Energy-releasing * ________- Nonspontaneous endergonic * **Endergonic: **Energy-absorbing * _________- Equilibrium
∆G < 0 ∆G > 0 ∆G = 0
70
# LAWS OF THERMODYNAMICS First and the second laws can be related to the free energy by an equation
△G = △H −T△S
71
# LAWS OF THERMODYNAMICS changes in enthalpy
△H
72
Heat of a reaction at constant pressure
Enthalpy
73
the changes in entropy
△S
74
the changes in free energy
△G
75
the temperature
T