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BIOL 3155 > Chapter 1 > Flashcards

Chapter 1 Flashcards

Introduction to Virology

1
Q

Acquired Immunodeficiency Syndrome

A

HIV-1 / Retrovirus

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2
Q

Cervical carcinoma

A

HPV types 16, 18, 31 / Papillomavirus

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3
Q

Cold sores

A

HSV type 1 / Herpesvirus

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4
Q

Common cold

A

Adenoviruses; Coronaviruses; Rhinoviruses

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5
Q

Genital Herpes

A

HSV type 2 / Herpesvirus

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6
Q

SARS

A

SARS coronavirus / Coronavirus

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7
Q

Warts

A

HPV types 1, 2, 4

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8
Q

Yellow fever

A

Yellow fever virus / Flavivirus

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9
Q

Rabies vaccine (1885)

A

Pasteur

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10
Q

Filtered tobacco mosaic virus (1892 & 1898)

A

Ivanovski & Beijerinck

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11
Q

Filtered foot-and-mouth disease (1898)

A

Loeffler and Frosch

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12
Q

Smallpox vaccine (1797)

A

Jenner

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13
Q

Crystallization of tobacco mosaic virus (1935)

A

Stanley and Northrup

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14
Q

Studies with bacteriophages (1940s)

A

Delbruck and Luria

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15
Q

Growth of poliovirus in cultured cells (1949)

A

Edners, Robbins, Weller

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16
Q

Filtered yellow fever virus (1900)

A

Finlay and Reed

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17
Q

Discovery of interferon (1957)

A

Isaacs and Lindenmann

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18
Q

Poliovirus vaccines: killed (1955) and live (1960)

A

Salk and Sabin

19
Q

Reverse transcriptase in retroviruses (1971)

A

Temin and Baltimore

20
Q

Bacteriophage genes are DNA (1952)

A

Hershey and Chase

21
Q

Cellular oncogen is part of a retrovirus genome (1976)

A

Bishop and Varmus

22
Q

RNA splicing in adenovirus (1977)

A

Sharp and Roberts

23
Q

Prions as infectious proteins (1975-1990)

A

Prusiner

24
Q

Virus vectors and genetic engineering (1970s)

A

Berg

25
Q

Discovery of AIDS virus (1983)

A

Montagnier and Barre-Sinoussi

26
Q

Plaque assay

A

to count the number of infectious virus particles in a suspension

27
Q

Hemagglutination assays

A

a method of titering viruses that agglutinate red blood cells

28
Q

HPV cause cervical cancer (1972-1984)

A

Hausen

29
Q

Envelop

A

a lipid membrane that, in some cases, encloses the capsid

30
Q

Virion

A

an infectious virus particle

31
Q

Obligatory intracellular parasites

A

viruses multiply inside cells by expressing and replicating their genomes

32
Q

Casid

A

a protein coat that encloses the genome

33
Q

Hemorrhagic fevers

A

Dengue virus / Flavivirus

34
Q

Hepatits

A

Picornavirus / Hepadnavirus / Flavivirus

35
Q

Influenza

A

Influenza A and B virus / Orthomyxovirus

36
Q

Four cellular machineries needed

A

synthesize polymers; generate usable chemical energy; protein synthesis; membranes for ions and macromolecules

37
Q

Baltimore classification for (+) ss-RNA

A

1 -> early protein

38
Q

Baltimore classification for (-) ss-RNA

A

2 -> vRdRp

39
Q

Baltimore classification for ds-RNA

A

3 -> vRdRp

40
Q

Baltimore classification for ds-DNA

A

4 -> DdRp

41
Q

Baltimore classification for ss/ds-DNA

A

7 -> DpDp (RT) -> DdRp

42
Q

Baltimore classification for ss-DNA

A

5 -> DpDp (RT) -> DdRp

43
Q

Baltimore classification for (+) ss-RNA (RT)

A

6 -> vRdDp (RT) -> DdDp -> DdRp

BIOL 3155 (16 decks)

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