Chapter 1-3 Flashcards
An animal that was cesarean derived and lived its entire life in a sterile, controlled environment would be classified as
barrier sustained
the range of temperature when an animal does not need mechanisms to produce or lose heat is
thermoneutral zone
Examples of experimental factors that predispose an animal to disease are
surgery, restraint and drugs
the term that refers to ensuring the experimental procedure causes the least amount of stress, pain, anxiety, and disturbance to the normal life of the animla and still reaches the goal
refinement
How often should the facility be inspected and the program of veterinary care be reviewed by IACUC?
every 6 months
developing a new surgical procedure would be defined as
applied research
adding a reting ledge to a cage for a cat would be an example of
environmental enrichment
in every animal room in this type of facility there are 2 doors, one for entering and one for exiting. What facility is this?
double corridor facility
The FDA mandates all new medications undergo which type of testing?
clinical research
What is the highest level of certification in the members listed in the research team?
PI
A researcher is interested in acquiring animals tat are free of certain pathogens but is not too concerned if the animal has additional pathogens other than those specified.
specific pathogen free
individuals that like to hunt, fish, raise livestock, or go to zoos would fall into what category?
animal use group
dietary factors can have an effect on an animal and predispose it to diseases. What dietary factors?
food, water quality and water container sanitation
An animal that is delivered naturally but has lived its entire life in a sterile, controlled environment would be classified as
axenic
which area of a facility must have temperature and humidity control and contain shelves or pallets?
feed storage
which type of research much be conducted on live animals
clinical research
federal organizations that write and enforce laws regarding animals would be members of what group?
animal control groups
the primary reference on animal care and use is the
Guide for the Care and Use of Laboratory Animals
which organization promotes the humane treatment of animals in science through a voluntary accreditation program
AAALAC
which area of the animal facility should have a clean and dirty side and be as far away from the animal rooms as possible?
cage washing room
when considering the primary enclosures used for a specific species, which of the following is NOT a consideration
capable of holding as many animals as possible
A researcher is proposing a study using Mycobacterium tuberculosis. What lvl of biosafety would be required?
biosafety lvl 3
what entity is responsible for all aspects of animal use, education, health and compliance with the laws and regulations within a facility?
IACUC
When working with Ebola virus, what lvl of biosafety is required?
biosafety lvl 4
a postsurgical patient should be placed in what typ of cage?
recovery cage
the term laboraty animal refers to
any animal used in research or teaching
a theory based on current knowledge that could answer a specific question or provide a solution is called a
hypothesis
when a scientist has deduced that an experimental model could be conducted on tissue cultures instead of rats would be an example of
replacement
temperature, humidity, lighting, and ventilation within a facility comprise the
macroenvironment
the legal definition of an exotic pet refers to
any animal that is not native to the area where it is being housed
the organization respsponsible for enforcing laws that protect workers from workplace hazards
OSHA
research that is concerned with advancing the fundamental knowledge of physical, chemical and fucntional mechanisms of life processes and disease is
basic research
the research team leader is the
PI
a researcher needs animals that have well defined microflora with specific organisms and only microorganisms present. How are they calssified?
gnotobiotic
an individual who firmly believes that animal research should never be done no matter what the purpose or value would be a mamber of which group?
animal rights group
the organization that certifies laboratory animal veterinarians is the
ACLAM
a research protocol requires the collection of urine and feces to access the total volume produced per animal per day
metabolism cages
which type of facility contains an airlock in the entrance and may have UV lights within the airlock to sterilize equipment and supplies
barrier facility
a research study involving a vaccine for canine infectious hepatitis virus would be considered a
biosafety lvl 3
the temp, humidity, lighting and ventilation of cages at the bottom of the rack of cages may be different from those at the top of the rack
microenvironment
a facility needs new caging for dogs, what is teh strongest material that is resistant to rust and cleaning agents
stainless steel
an individual that advocates animals should not be forced to work or produce for human benefit in any way and believe animals should not be owned by a person are members of which group?
animal liberation group
an individual who believes that animals are stricly to be used by humans, who believes animals don’t feel pain, or who has no concern for the animal if it was in pain would likely be a member of an
animal exploitation group
extrinsic predisposing factors are
temp, humidity, lighting and noise
predisposing factors referred to as intrinsic factors that can affect animal health are
species, age, gender, and heredity
animals that have highly zoonotic or infectious diseases should be housed in what type of facility
containment facility
the use of the absolute least number of animals that will achieve the research goals is referred to as
reduction
animals that are germ free are generally housed in what type of facility
barrier
a research protocol that involves salmonella organisms would be considered
biolsafety lvl 3
if an owner of an exotic pet is no longer able to care for the animal the vet team should assist the owner by
helping them find a new home, zoo, or sanctuary for the pet
a method of quality assurance in an animal facility is to periodically collect serologic, fecal, and blood testing to id the presence of microorganisms. What type of animals are used for this testing?
sentinel
what is the first lvl of certification for members of the research team
alat
most animal rooms can be maintained with what range of relative humidity
45-55%
when an experiment can be conducted using a lower life form, a computer model, or artificial means it is referred to as
replacement
an animal room used to quarantine infectioius animals should be maintained with
negative air psi
an animal that is acquired from a USDA class A dealer would be known as
purpose bred
a shoebox rodent cage usually contains a specific lid designed for feeding. What type of feeder is used?
v-shaped
a new animal facility is being planned. what is the most important aspect of the design process
designed to minimize the spread of disease from one part of the facility to another
what is the minimum number of people that can be on the IACUC?
3
what is the recommended type of light system for animal rooms
diurnal illumination
