chapter 1 Flashcards
father of western medicine
hippocates
first recorded physicain
Imhotep
architect of pyramids, medicine, poetry
god of medicine
the rod of asclepius
mixed up with the caduceus-the rod of Hermes-the greek messenger god-used as trade symbol
materia medica
greek physician Dioscorides
first medical textbook in europe
father of toxicology
paracelsus
the dose makes the poison
clark stanley snake oil
early 1900s reported to cure chili blains, cancer, consumption
control of “worthless” claims by clinical drug trails
pharmacodynamics
what the drug does to the body
what most clinicians are concerned with
pharmacokinestics
what the body does to the drug
half life, barrier crossing
pharmacogenomics
genetic profile to determine how your going to respond to the drug
toxicology
undesirable effects of chemicals on living systems
agonist vs antagonist
has a response from the receptor when it binds
blocks the ligand from binding/blocks the receptor
allosteric vs orthostatic
toxins vs posions
TOXIN
-biological in substance from living organisms
- puffer fish, mushrooms
POISONS
- non-biological
- arsenic, lead, cadmium
orthostatic vs allostatic
ORTHOSTATIC
- active site
ALLOSTATIC
- binding outside the active site
toxicology