Chapter 1 Flashcards
disease
any disturbance in function or structure of body
acute illness
short term/sudden onset
decreases w/age
chronic illness
long lasting (>6mo)
increases w/age
idiopathic
unknown cause of disease
etiology
cause of disease
pathogenesis
formation (history and development) of disease
nosocomial
cause of disease is from hospital
iatrogenic
cause of disease is secondary to medical procedure
incidence
number of new cases
prevalence
total number of cases
sensitivity
true positive rate
specificity
true negative rate
sign
can be measured, objective
ie. blood pressure, fever
symptom
can be felt, subjective, immeasurable
ie. nausea, stomach ache,
relationship between structure and function in terms of disease
structural disease: something happens to the structure of something
functional disease: something functionally goes wrong (hypertension, mental health)
abnormal vs. normal
normal parameters vs. parameters measured outside of normal
sick vs. healthy
presence or absence of disease
does not deal with signs or symptoms
normal values of diagnostic test
how far away are you from normal range
characteristics of a good screening test
inexpensive, safe, easy, noninvasive
screening test vs. diagnostic test
screening tests are used in patients with no signs or symptoms vs. diagnostic tests used in patients at risk for certain disease or those w/symptoms
how to calculate sensitivity
number of true positives/total number with illness
how to calculate specificity
number of true negatives/total number without illness
how to calculate positive predictive value
true positive/(true positive+false positives)
how to calculate negative predictive value
true negative/(true negative+false negative)
how does disease prevalence influence a diagnostic test?
if the prevalence is high, tests should be run; but if low prevalence, there is no need for diagnostic testing
palliative care
special treatment where disease is managed and cured
hospice care
comforting help to patient where disease cannot be cured, specifically used to manage and comfort pt