Chap 83 Wound Care Flashcards

1
Q

List causes of non-healing wounds and name one method of investigation for each.

A

Venous hypertension–Plethysmography/Doppler

Arterial insufficiency–NIVs (macro), tcPO2/biopsy (micro)

Bacterial colonization–wound culture or biopsy

Malignancy–biopsy

Lymphatic obstruction–clinical, lymphangiography

Hematological disorders–B/W

Collagen vascular disorders–serum markers

Excessive pressure—vibratory sensation (>25mV)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the stage of normal wound healing.

A

inflammatory
proliferative
epithelialization and remodelling

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Describe the inflammatory phase.

A

Mediated by Mast cells, neutrophils, macrophages
Release cytokines that recruit fibroblast and epithelial cells
Within 24hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Describe the proliferative phase.

A

Macs—growth factors that begin angiogenesis

Finroblast and cytokines synthesize collagen and proteoglycans—granulation tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Describe the Epithelialization and remodelling phase

A

Epithelial cells migrate into the wounds, secret MMP to degrade nonviable tissue
Remodeling long-term procee where type III collagen replaces type I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

List mechanisms of abnormal wound healing

A

Inflammation
Inflam cause up regulation of cytokins and MMP which has a detrimental effect because they are present persistently

Cytokines
Upregulation of THN-alpha, IL-1, IL-6

Cell senescence
Cells have diminished response to agonist-induced proliferation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the National Pressure Ulcer Advisory Panel Staging of ulcers?

A

Stage I Non-blacheable erythema
Stage II partial thickness (partial dermis)
Stage III Full thickness skin loss
Stage IV full thickness tissue loss (bone, tendon, muscle)
Unstageable–until eschar comes off)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

List forms of non-vaible tissue.

A

callus
eschar
fibrinous material
slough

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

List methods of debridement and examples.

A

mechanical–surgical, best
chemical-collagenase
larval-maggots
US

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

When to treat bacterial colonization?

A

when counts are > 10 5th power counts per cubic millimeter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Give an example, advantages/disadvantage and e.g. of when to use gauze.

A

kerlix

debridement
absorptive
cheap

may dehydrate wound
damage granulation tissue
frequent changes

infected wounds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Give an example, advantages/disadvantage and e.g. of when to use film.

A

tegaderm
opsite

semipermeable
retains moisture
waterproof
visualization of wound

can’t use on infected wounds
may tear skin

post-surgical wounds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Give an example, advantages/disadvantage and e.g. of when to use hydrogel.

A

nu-gel

rehydrate wound
extends time b/w dressing changes
fills dead spar

may be difficult to secure secondary dressing
may macerate skin

diabetic foot ulcers
minimally exudative wounds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Give an example, advantages/disadvantage and e.g. of when to use hydrocolloid.

A

duoderm
tagasorb

impremeable to bacteria
facilitates autolytic debridement
self-adhesive

not for infected or exudative wounds
may cause skin tears

patialthickness wounds
low-exudative pressure ulcers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Give an example, advantages/disadvantage and e.g. of when to use foam.

A

allevyn

highly absorptive
protective

may macerate
secondary dressing
not effective for dry wounds

highly exudative wounds
venous ulcers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Give an example, advantages/disadvantage and e.g. of when to use alginate.

A

algisite

forms moist gel in wound
highly absorptive
controls heavy exudate

can dehydrate wound
secondary dressing

heavily exudative wounds
venous ulcers

17
Q

what are diabetic wounds best treated with?

A

donate moisture like hydrogels

18
Q

What are draining wounds best treated with

A

alginates

19
Q

what is the evidence for silver impregnated dressing for colonized wounds?

A

does not heal better then without

20
Q

What is the evidence for compression and pentoxifylline for leg ulcer?

A

MA.

combo results in faster healing

21
Q

What is the evidence for vein stripping in leg ulcers?

A

RCT showed at 4 years, stripping + compression 31% had recurrence, vs 56% with compression alone
Venous stripping reasonable when superficial venous reflux is a prominent compoenet (30-50%)

22
Q

What is the evidence for skin grafting?

A

there is non to show better

can get recurrence

23
Q

What is evidence for VAC therapy?

A

RCT–accelerates wound healing

24
Q

Hoe does VAC therapy work?

A

negative pressure

Removal of exudate, stimulation of senescent cells, mobilization of macrophages, stimulation of angiogenesis

25
Q

How does hyperbaric O2 therapy work?

A

100% oxygen at elevated atmospheric pressure
increase partial pressure of oxygen in tissues
improve oxygen supply, reduction of inflammation and edema, inhibition of infection, stimulate angiogenesis, enhance fibroblast function
one treatment daily for total of 20-40 treatments

26
Q

What is the evidence for hyperbaric O2 therapy?

A

limited for ischemic limbs