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Organ Histo > Chap 3 Part 1 > Flashcards

Chap 3 Part 1 Flashcards

1
Q

What are the 2 main functions of Cartilage?

A

support and serves as a template for endochondral bone ossification

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2
Q

What are the 3 types of cartilage?

A

hyaline, elastic and fibrocartilage

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3
Q

Which type of cartilage is primarily collagen II fibers?

A

hyaline

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4
Q

Which type of cartilage is primarily elastic and collagen II?

A

elastic

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5
Q

Which type of cartilage is primarily collagen I and some collagen II?

A

fibrocartilage

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6
Q

What kind of cartilage is found in the the nasal cartilage?

A

hyaline

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7
Q

What kind of cartilage is found in the epiglottis?

A

elastic

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8
Q

What kind of cartilage is the pubic symphysis?

A

fibrocartilage

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9
Q

What are the 4 main components of the ground substance of hyaline cartilage matrix?

A

aggrecans, hyaluronic Acid, other proteoglycans, and chondronectin

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10
Q

What two things make up the matrix of hyaline cartilage?

A

ground substance and fibers (primarily Collagen II)

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11
Q

What are aggrecans?

A

large molecules composed of proteins and sulfated GAGs

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12
Q

What are the 3 types of cells associated with hyaline cartilage?

A

chondrogenic cells, chondroblasts, and chondrocytes

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13
Q

Which cells associated with hyaline cartilage appear very narrow, are derived from mesenchyme cells and sometimes osteoprogenitor cells, undergo mitosis and function as a source of chondroblasts?

A

chondrogenic cells

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14
Q

what do chondrogenic cells differentiate into?

A

chondroblasts or mature osteoprogenitors

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15
Q

where are chondrogenic cells located?

A

chondrogenic perichondrium

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16
Q

Which cells associated with hyaline cartilage differentiate into chondrocytes, produce the matrix, and have a lower nutrient requirement that allows them to be inactive for long periods of time?

A

chondroblasts

17
Q

Which cells associated with hyaline cartilage are rounder and larger, located interior to the perichondrium, do not differentiate, and function to maintain the matrix/prevent calcification?

A

chondrocyte

18
Q

which cell associated with hyaline cartilage probably does not undergo mitosis (but maybe)?

A

chondrocyte

19
Q

T/F: chondrocytes live within a lacuna and have a very high nutrient requirement.

A

False; they do live in a lacuna but have a very low nutrient requirement; sometimes they exist in isogenic groups

20
Q

Chondrocytes can sometimes secrete territorial matrix. How is territorial matrix different from regular matrix?

A

higher in GAGs and lower in fibers

21
Q

Where is the perichondrium? exceptions?

A

peripheral to cartilage; epiphyseal growth plates and articular cartilage

22
Q

What are the two parts of the perichondrium?

A

fibrous perichondrium and chondrogenic perichondrium

23
Q

What is the primary cell type of the fibrous perichondrium? primary fiber type?

A

fibroblast; collagen I

24
Q

T/F:fibrous perichondrium is avascular.

A

False; chondrogenic perichondrium is avascular

25
Q

T/F: Chondrogenic perichondrium is located between fibrous perichondrium and mature cartilage.

A

True

26
Q

What is the primary cell type of chondrogenic perichondrium? primary fiber type?

A

chondrogenic cells and chondroblasts; collagen II

27
Q

What is perichondrium a source of and why is this important?

A

source of chondrogenic cells and chondroblasts which leads to more cells and matrix produced

28
Q

T/F: all original cartilage develops from embryonic mesenchyme tissue.

A

True

29
Q

What begins with a grouping of rounded mesenchymal cells that can be called a chondrogenic nodule located towards the center of the developing tissue?

A

Interstitial Cartilage Growth

30
Q

Do chondroblasts divide within the chondrogenic nodule during interstitial cartilage growth?

A

yes

31
Q

What secretes matrix during interstitial cartilage growth?

A

chondroblasts

32
Q

What happens to secretion (during interstitial growth) after enough matrix concentrate or sets up?

A

secretion stops

33
Q

During interstitial cartilage growth:

What do chondrocytes develop from? When they divide what do they create? What kind of new matrix will they secrete?

A

chondroblasts; isogenous groups; territorial

34
Q

What is the stopping point of cartilage development?

A

chondrogenic perichondrium

35
Q

Where does interstitial cartilage growth take place?

A

epiphyseal growth plates, and articular cartilage

Organ Histo (7 decks)

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