Chap 2 Part 2 Flashcards
What are the 4 events mediated by mast cells?>
asthma, anaphylaxis, immediate hypersensitivity response (simple allergy), and basic inflammatory reaction (cut in the skin)
What are the 5 parts of the basic inflammatory reaction?
stimulus, mast cells degranulating, histamine, then leukotrienes, and Heparin/ECF react last
What is the stimulus for the basic inflammatory reaction?
phagocytosis (ex. dead cells, debris, or broken fibers)
What are the 3 parts of the Immediate Hypersensitivity Response?
stimulus, mast cells degranulating, and localized inflammatory response
What is the stimulus for the immediate hypersensitivity response?
IgE and Allergins (ex. hay fever and contact dermitis)
What condition is described as leaky capillaries and venules below epithelium leading to urticaria (hives) and “weepy skin”
contact dermitis
What are the 4 parts of Anaphylaxis?
stimulus, systemic mast cell and basophil degranulation, systemic inflammatory response, and anaphylactic shock
What causes anaphylactic shock?
extensive internal blood loss
What is the stimulus for anaphylaxis?
massive IgE production
Which type of asthma is typically adult onset?
intrinsic asthma
Which type of asthma is typically childhood onset?
extrinsic asthma
Which type of asthma may follow a respiratory illness and the allergin is typically unknown?
intrinsic asthma
What stimulates asthma?
IgE allergin complex and/or secondary factors such as fatigue, emotion, temperature, food, endocrine changes
What is the primary problem of asthma?
release of leukotrienes leads to contraction of smooth muscles in the bronchioles leading to their closing
What is the secondary problem with asthma?
inflammation in the lungs