Chap 2 Part 2 Flashcards
What are the 4 events mediated by mast cells?>
asthma, anaphylaxis, immediate hypersensitivity response (simple allergy), and basic inflammatory reaction (cut in the skin)
What are the 5 parts of the basic inflammatory reaction?
stimulus, mast cells degranulating, histamine, then leukotrienes, and Heparin/ECF react last
What is the stimulus for the basic inflammatory reaction?
phagocytosis (ex. dead cells, debris, or broken fibers)
What are the 3 parts of the Immediate Hypersensitivity Response?
stimulus, mast cells degranulating, and localized inflammatory response
What is the stimulus for the immediate hypersensitivity response?
IgE and Allergins (ex. hay fever and contact dermitis)
What condition is described as leaky capillaries and venules below epithelium leading to urticaria (hives) and “weepy skin”
contact dermitis
What are the 4 parts of Anaphylaxis?
stimulus, systemic mast cell and basophil degranulation, systemic inflammatory response, and anaphylactic shock
What causes anaphylactic shock?
extensive internal blood loss
What is the stimulus for anaphylaxis?
massive IgE production
Which type of asthma is typically adult onset?
intrinsic asthma
Which type of asthma is typically childhood onset?
extrinsic asthma
Which type of asthma may follow a respiratory illness and the allergin is typically unknown?
intrinsic asthma
What stimulates asthma?
IgE allergin complex and/or secondary factors such as fatigue, emotion, temperature, food, endocrine changes
What is the primary problem of asthma?
release of leukotrienes leads to contraction of smooth muscles in the bronchioles leading to their closing
What is the secondary problem with asthma?
inflammation in the lungs
What are the 5 types of leukocytes discussed in class?
monocytes, neutrophils, eosinophils, basophils, and lymphocytes
Which type of leukocyte is attracted to sites of acute inflammation and also the most numerous of the leukocytes?
neutrophils
Which type of leuokcyte is attracted to sites of allergy inflammation? chronic inflammation sites?
eosinophils; lymphocytes
What are mesenchyme cells?
adult stem cells
T/F: mesenchyme cells increase with age.
False; they decrease with age
What are reticular cells derived from?
mesenchyme cells
What is the functuon of reticular cells?
to make reticular fibers when needed on a permanent basis
What are the 2 classifications of CT?
CT proper and specialized CT
What are the 4 types of CT proper?
loose CT, dense CT, reticular CT and adipose
Which type of CT proper has a larger number of cells/cell types, fewer fibers, increased GAGs, and is quite vascular?
Loose CT
What are the 2 types of Loose CT?
loose areolar and loose irregular
Which type of CT proper has fewer cells/cell types, many fibers, decreased amounts of ground substance and are less vascular?
Dense CT
What are the 2 types of Dense CT?
dense irregular and dense regular
Which type of CT proper can be found in lymphatic and endocrine organs?
Reticular CT
Which highly vascular type of CT proper functions as an energy source, cushion organ, and a thermoregulator?
adipose
An increase in cell types should lead to what?
an increase in healing potential
An increased vascularity should lead to what?
increased healing potential
What are the 3 types of Specialized CT?
Cartilage, bone and blood
