Chap 2 Part 2 Flashcards

1
Q

What are the 4 events mediated by mast cells?>

A

asthma, anaphylaxis, immediate hypersensitivity response (simple allergy), and basic inflammatory reaction (cut in the skin)

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2
Q

What are the 5 parts of the basic inflammatory reaction?

A

stimulus, mast cells degranulating, histamine, then leukotrienes, and Heparin/ECF react last

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3
Q

What is the stimulus for the basic inflammatory reaction?

A

phagocytosis (ex. dead cells, debris, or broken fibers)

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4
Q

What are the 3 parts of the Immediate Hypersensitivity Response?

A

stimulus, mast cells degranulating, and localized inflammatory response

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5
Q

What is the stimulus for the immediate hypersensitivity response?

A

IgE and Allergins (ex. hay fever and contact dermitis)

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6
Q

What condition is described as leaky capillaries and venules below epithelium leading to urticaria (hives) and “weepy skin”

A

contact dermitis

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7
Q

What are the 4 parts of Anaphylaxis?

A

stimulus, systemic mast cell and basophil degranulation, systemic inflammatory response, and anaphylactic shock

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8
Q

What causes anaphylactic shock?

A

extensive internal blood loss

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9
Q

What is the stimulus for anaphylaxis?

A

massive IgE production

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10
Q

Which type of asthma is typically adult onset?

A

intrinsic asthma

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11
Q

Which type of asthma is typically childhood onset?

A

extrinsic asthma

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12
Q

Which type of asthma may follow a respiratory illness and the allergin is typically unknown?

A

intrinsic asthma

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13
Q

What stimulates asthma?

A

IgE allergin complex and/or secondary factors such as fatigue, emotion, temperature, food, endocrine changes

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14
Q

What is the primary problem of asthma?

A

release of leukotrienes leads to contraction of smooth muscles in the bronchioles leading to their closing

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15
Q

What is the secondary problem with asthma?

A

inflammation in the lungs

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16
Q

What are the 5 types of leukocytes discussed in class?

A

monocytes, neutrophils, eosinophils, basophils, and lymphocytes

17
Q

Which type of leukocyte is attracted to sites of acute inflammation and also the most numerous of the leukocytes?

A

neutrophils

18
Q

Which type of leuokcyte is attracted to sites of allergy inflammation? chronic inflammation sites?

A

eosinophils; lymphocytes

19
Q

What are mesenchyme cells?

A

adult stem cells

20
Q

T/F: mesenchyme cells increase with age.

A

False; they decrease with age

21
Q

What are reticular cells derived from?

A

mesenchyme cells

22
Q

What is the functuon of reticular cells?

A

to make reticular fibers when needed on a permanent basis

23
Q

What are the 2 classifications of CT?

A

CT proper and specialized CT

24
Q

What are the 4 types of CT proper?

A

loose CT, dense CT, reticular CT and adipose

25
Q

Which type of CT proper has a larger number of cells/cell types, fewer fibers, increased GAGs, and is quite vascular?

A

Loose CT

26
Q

What are the 2 types of Loose CT?

A

loose areolar and loose irregular

27
Q

Which type of CT proper has fewer cells/cell types, many fibers, decreased amounts of ground substance and are less vascular?

A

Dense CT

28
Q

What are the 2 types of Dense CT?

A

dense irregular and dense regular

29
Q

Which type of CT proper can be found in lymphatic and endocrine organs?

A

Reticular CT

30
Q

Which highly vascular type of CT proper functions as an energy source, cushion organ, and a thermoregulator?

A

adipose

31
Q

An increase in cell types should lead to what?

A

an increase in healing potential

32
Q

An increased vascularity should lead to what?

A

increased healing potential

33
Q

What are the 3 types of Specialized CT?

A

Cartilage, bone and blood