Chap 21 - Pharmacology Textbook Flashcards
addiction
Physical and psychological dependence on and craving for a drug.
additive action
Drug action in which the combination of two similar drugs is equal to the sum of the effects of each. ( 1+1=2 )
aerosol
Particles of drug suspended in air.
anaphylaxis
Exaggerated hypersensitivity reaction to a previously encountered drug or foreign protein. (local or systemic)
antagonistic action
Combination of two drugs gives LESS THAN an additive effect (action).
antidote
Agent given to counteract an unwanted effect of a drug.
brand name
trademark or trade name of drug manufacturer
chemical name
exact chemical makeup
contraindications
Factors that prevent the use of a drug or treatment.
controlled substances
Drugs that produce tolerance and dependence and have potential for abuse or addiction.
dependence
Physiologic need for a drug due to prolonged use.
dose
Amount of drug administered, milligrams.
Food and Drug Administration (FDA)
U.S. government agency having the legal responsibility for enforcing proper drug manufacture and clinical use.
generic name
Legal noncommercial name for a drug.
iatrogenic
Condition caused by treatment (drugs or procedures) given by physicians or medical personnel.
idiosyncratic reaction
Unexpected effect produced in a particularly sensitive patient but not seen in most people.
inhalation
Administration of drugs in gaseous or vapor form through the nose or mouth.
medicinal chemistry
Study of new drug synthesis; relationship between chemical structure and biological effects.
molecular pharmacology
Study of interaction of drugs and their target molecules such as enzymes, or cell surface receptors.
oral administration
Drugs are given by mouth
parenteral administration
Drugs are given by injection into the skin, muscles, or veins - OUTSIDE of the GI tract
pharmacist
Specialist in preparing and dispensing drugs.
pharmacy
Location for preparing and dispensing drugs; also the study of preparing and dispensing drugs.
pharmacodynamics
Study of drug effects within the body.
pharmacokinetics
Study of drug absorption, distribution, metabolism, and excretion over a period of time
pharmacologist
Specialist in the study of the properties, uses, and side effects of drugs.
pharmacology
Study of the preparation, properties, uses, and side effects of drugs.
Physicians’ Desk
Reference (PDR)
Reference book that lists drug products.
PAID ADVERTISMENT
receptor
Target substance with which a drug interacts in the body.
rectal administration
Drugs are inserted through the anus into the rectum.
resistance
Lack of beneficial response
response
Desired and beneficial effect of a drug.
schedule
Exact timing and frequency of drug administration.
side effect
Adverse reaction, usually minor, that routinely results from the use of a drug.
sublingual administration
Drugs are given by placement under the tongue.
synergism (potentiation)
Combination of two drugs causes an effect that is greater than the sum of the individual effects of each drug alone. (1+1=3)
syringe
Instrument (tube) for introducing or withdrawing fluids from the body.
tolerance
waning action over time
topical application
Drugs are applied locally on the skin or mucous membranes of the body
toxicity
Harmful effects of a drug
toxicology
Study of harmful chemicals and their effects on the body.
transport
Movement of a drug across a cell membrane into body cells.
United States Pharmacopeia (USP)
Authoritative list of drugs, formulas, and preparations that sets a standard for drug manufacturing and dispensing.
vitamin
Substance found in foods and essential in small quantities for growth and good health.
ACE inhibitor
Lowers blood pressure. Angiotensin-converting enzyme (ACE) inhibitors block the conversion of angiotensin I to angiotensin II (a powerful vasoconstrictor).
CARDIO
amphetamine
CNS stimulant
analgesic
relieves pain
androgen
male hormone
ENDO
anesthetic
reduces or eliminates sensation; general and local
angiotensin II receptor blocker (ARBs)
Lowers BP by preventing angiotensin from acting on receptors in blood vessels.
CARDIO
antacid
neutralizes acid in the stomach
GI
antiandrogen
Slows the uptake of androgens or interferes with their effect in tissues
ENDO
antiarrhythmic
Treats abnormal heart rhythms.
CARDIO
antibiotic
Chemical substance, produced by a plant or microorganism, that has the ability to inhibit or destroy foreign organisms in the body.
Ex - antifungals, cephalosporins, erythromycin, tetracycline,
antituberculars, penicillins, quinolones, and sulfonamides.
anticoagulant
prevents blood clotting
anticonvulsant
prevents convulsions
antidepressant
relieves symptoms of depression
antidiabetic
Drug given to prevent or treat diabetes mellitus.
antidiarrheal
prevents diarrhea
GI
antiemetic
prevents nausea and vomiting
antihistamine
Blocks the action of histamine and helps prevent symptoms of allergy.
antinauseant
Relieves nausea and vomiting; antiemetic.
GI
antiplatelet
Reduces the tendency of platelets to stick together and form a clot.
antiulcer
Inhibits the secretion of acid by cells lining the stomach.
GI
antiviral
Acts against viruses such as herpesviruses and HIV.
aromatase inhibitor
Reduces estrogen in the blood by blocking the enzyme aromatase.
bactericidal
Kills bacteria
bacteriostatic
Inhibits bacterial growth
beta-blocker
Blocks the action of epinephrine at sites on receptors of heart muscle cells, the muscle lining of blood vessels, and bronchial tubes; antiarrhythmic, antianginal, and antihypertensive.
CARDIO
bisphosphonate
prevents bone loss in osteoporosis
caffeine
CNS stimulant
calcium channel blocker (calcium antagonist)
Blocks the entrance of calcium into heart muscle and muscle lining of blood vessels; used as an antiarrhythmic, antianginal, and antihypertensive.
CARDIO
cardiac glycoside
Increases the force of contraction of the heart.
cardiovascular drug
Acts on the heart and blood vessels. This category of drug includes ACE inhibitors, beta-blockers, calcium channel blockers, cholesterol lowering drugs or statins, and diuretics.
cathartic
Relieves constipation.
GI
cholesterol-binding drug
Binds to dietary cholesterol and prevents its uptake from the GI tract.
cholesterol-lowering drug
Lowers cholesterol by preventing its production by the liver; statin.
CARDIO
diuretic
Increases the production of urine and thus reduces the volume of fluid in the body; antihypertensive.
CARDIO
emetic
promotes vomiting
endocrine drug
hormone or hormone-like drug
Ex - androgens, estrogens,
progestins, SERMs, thyroid hormones, and glucocorticoids.
estrogen
Female hormone that promotes development of secondary sex characteristics and supports reproductive tissues.
ENDO
gastrointestinal drug
Relieves symptoms of diseases in the gastrointestinal tract.
Ex - antacids, antiulcer drugs, antidiarrheal drugs, cathartics, laxatives,
purgatives, and antinauseants (antiemetics).
glucocorticoids
Hormone from the adrenal cortex that raises blood sugar and reduces inflammation.
ENDO
hypnotic
produces sleep or a trace-like state
laxative
weak cathartic
GI
narcotic
Habit-forming drug (potent analgesic) that relieves pain by producing stupor or insensibility; morphine and opium are examples.
progestin
Female hormone that stimulates the uterine lining during pregnancy and is also used in treatment of abnormal uterine bleeding and for hormone replacement therapy.
ENDO
prugative
relieves constipation; strong cathartic
respiratory drug
Treats asthma, emphysema, and infections of the respiratory system. (Bronchodilators)
sedative
A mildly hypnotic drug that relaxes without necessarily producing sleep. (Benzodiazepines)
stimulant
Excites and promotes activity. (caffeine, amphetamines)
thyroid hormone
Stimulates cellular metabolism.
ENDO
tranquilizer
Controls anxiety and severe disturbances of behavior.
aer/o
air
alges/o
sensitivity to pain
bronch/o
bronchial tube
chem/o
drug
cras/o
mixture
cutane/o
skin
derm/o
skin
erg/o
work
esthes/o
feeling, sensation
hist/o
tissue
hypn/o
sleep
iatr/o
treatment
lingu/o
tongue
myc/o
mold, fungus
narc/o
stupor
or/o
mouth
pharmac/o
drug
prurit/o
itching
pyret/o
fever
thec/o
sheath (of brain and spinal cord)
tox/o, toxic/o
poison
vas/o
vessel
ven/o
vein
vit/o
life
ana-
upward, excessive, again
anti-
against
contra-
against, opposite
par-
other than, apart from
syn-
together, with
Drugs
medicines/substances used to prevent or treat a condition or disease
Various sources
Plants: digitalis
Animals: hormones
Synthesized in lab: methotrexate
hospital formulary
gives info about characteristics of drugs and their clinical usage (application to patient care) as approved by that particular hospital.
by mouth
PO, p.o., po
sublingual
SL
rectal
R
parenteral
- intracavitary injection
- intradermal injection (ID)
- intramuscular injection (IM)
- intrathecal injection (think spinal)
- intravenous injection (IV)
- subcutaneous injection (SC)
Selective estrogen receptor modulator (SERM)
increase bone formation
ENDO
a.c., ac
before meals
ad lib
freely, as desired
APAP
Acetaminophen
ARB
Angiotensin II receptor blocker
b.i.d., bid
2x a day
c
with
caps
capsules
Cc
cubic centimeter
gm, g
gram
gtt
drops
h
hour
h.s., hs
at bedtime
H2 blocker
Histamine h2 receptor antagonist
HRT
hormone replacement therapy
INH
Isoniazid-antituberculosis agent
MAOI
Monoamine oxidase inhibitor
mg
milligram
ml, mL
milliliter
NPO
nothing by mouth
NSAID
Nonsteroidal anti-inflammatory drug
p
after
p.c., pc
after meals
PCA
Patient-controlled analgesia
p.r.n., prn
as needed, as necessary
Pt
patient
q
every
q.h., qh
every hour
q2h
every 2 hours
q.i.d., qid
4x a day
q.s., qs
sufficient quantity
qAM
every morning
qPM
every evening
Rx
prescription
s
w/o
Sig.
direction - how to take med
s.o.s
if it is necessary
SSRI
Selective serotonin reuptake inhibitor
tab
tablet
TCA
Tricyclic antidepressant
t.i.d., tid
3x a day
DO NOT USE LIST
U - units
IU - International Unit
q.d. - daily
q.o.d. - every other day
X.0 mg - write X mg
.X mg - write 0.X mg
MS - morphine sulfate
MgSO4 - magnesium sulfate
Warfarin (Coumadin)
Heparin
anticoagulants
Acetaminophen (Tylenol)
analgesic - mild
Lipitor
atorvastatin
cholesterol-lowering statin
Singulair
montelukast
antiallergy drug
Lexapro
escitalopram oxalate
antidepressant
Nexium
esomeprazole magnesium
antiulcer/anti-GERD
Synthroid
levothyroxine
hormone (thyroid gland)
Plavix
clopidogrel bisulfate
adenosine diphosphate (ADP) inhibitor
Toprol XL
metoprolol succinate
antihypertensive (beta-blocker)
Prevacid
lansoprazole
antiulcer/anti-GERD
Vytorin
simvastatin ezetimibe
cholesterol-lowering statin
Advair Diskus
cetirizine
antihistamine
Effexor XR
venlafaxine
extended release antidepressant
Protonix
pantoprazole
proton pump inhibitor
Diovan
valsartan
angiotension II receptor antagonist
Fosamax
alendronate
bone resorption inhibitor; calcium inhibitor
Zetia
ezetimibe
cholesterol-lowering statin
Crestor
rosuvastatin
cholesterol-lowering statin
Levaquin
levofloxacin
antibiotic
ProAir HFA
albuterol
bronchodilator
Celebrex
celecoxib
analgesic
Flomax
tamsulosin
alpha-adrenergic blocker
Norvasc
amlodipine
antihypertensive (calcium channel blocker)
Nasonex
mometasone
corticosteroid
Warfarin (Coumadin)
Anticoagulant
Blocks formation of several clot-forming factors in blood
Tissue-type plasminogen activator
tPA
Dissolves clots and is used to open vessels after myocardial infarction
Tricyclic antidepressants (TCAs) Selective serotonin reputable inhibitors (SSRIs)
Increases the action of neurotransmitters by blocking their removal (reputable) from the synapses
Monoamine oxidase inhibitors (MAOIs)
Increase the length of time neurotransmitters work by blocking monoamine oxidase, enzyme that normally inactivated neurotransmitters
Sulfonylureas
Lower the levels of glucose in the blood by stimulating production of insulin
Biguanides
Increase the body’s sensitivity to insulin and reduce the production of glucose by the liver
Alpha-glucosidase inhibitors
Temporarily block enzymes that digest sugars
Thiazolidinediones
Enhance glucose uptake into tissues
Meglitinides
Stimulate the beta calls in the pancreas to produce insulin
Calcitonin
Treat osteoporosis
Anti-TNF (tumor necrosis factor)
Rx used to treat autoimmune diseases - Crohn’s, rheumatoid arthritis
anti-emetics
stops vomiting
anti-anginal
stops chest pains