Chap 19 - Oncology Review Sheets Flashcards
loss of differentiation of cells and reversion to a more primitive cell type:
anaplasia
extending beyond the normal tissue boundaries:
infiltrative
having the ability to enter and destroy surrounding tissue:
invasive
spreading to a secondary site:
metastasis
replication of cells; two identical cells are produced from a parent cell
mitosis
change in the genetic material of a cell
mutation
genetic material within the nucleus that controls replication and protein synthesis
DNA
cellular substance (ribonucleic acid) that is important in protein synthesis
RNA
rays given off by the sun; can be carcinogenic
ultraviolet radiation
energy carried by a stream of particles from a radioactive source; can be carcinogenic
ionizing radiation
infectious agent that reproduces by entering a host cell and using the host’s genetic material to make copies of itself
virus
a region of genetic material found in tumor cells and in viruses that cause cancer
oncogene
an agent (hydrocarbon, insecticide, hormone) that causes cancer
chemical carcinogen
solid tumor
tumor composed of a mass of cells
adenoma
tumor of glandular tissue (benign)
adenocarcinoma
cancerous (malignant) tumor of glandular tissue
osteoma
tumor of bone (benign)
osteosarcoma
flesh (connective tissue) tumor of bone (malignant
mixed-tissue tumor
tumor composed of different types of tissue (both epithelial and connective tissues)
neoplasm
new formation (tumor)
neurofibromatosis
benign tumors of supportive tissue (neurofibromatosis)
benign
noncancerous
differentiation
specialization of cells
small nipple-like projections
papillary
abnormal formation of cells
dysplastic
localized growth of cells
carcinoma in situ
densely packed; containing fibrous tissue
scirrhous
pattern resembling small, microscopic sacs
alveolar
small round, gland-type clusters
follicular
variety of cell types
pleomorphic
lacking structures typical of mature cells
undifferentiated
spreading evenly throughout the tissue
diffuse
resembling epithelial cells
epidermoid
containing dead tissue
necrotic
mushrooming pattern of growth: tumor cells pile on top of each other
fungating
characterized by large, open, exposed surfaces
ulcerating
characterized by redness, swelling, and heat
inflammatory
growths are projections from a base; sessile and pedunculated tumors are examples
polypoid
tumors form large, open spaces filled with fluid; serous and mucinous tumors are examples
cystic
tumors resemble wart-like growths
verrucous
tumors are large, soft, and fleshy
medullary
A is a cancerous tumor composed of cells of epithelial tissue. An example of such a cancerous tumor is a/an:
carcinoma; thyroid adenocarcinoma, squamous cell carcinoma
A is a cancerous tumor composed of connective tissue. An example of such a cancerous tumor is a/an:
sarcoma; liposarcoma,
chondrosarcoma, osteogenic
sarcoma
Retinoblastoma and adenomatous polyposis coli syndrome are examples of:
inherited cancers
The assessment of a tumor’s degree of maturity or microscopic differentiation is ________ of the tumor.
grading
The assessment of a tumor’s extent of spread within the body is known as:
staging
In the TNM staging system, T stands for _______, N stands for ________, and M stands
for ________
tumor; node; metastasis
The transformation of adult, differentiated tissue to differentiated tissue of another type is called:
metaplasia
The formation of new blood vessels is known as:
angiogenesis
fulguration
destruction of tissue by electric sparks generated by
a high-frequency current
en bloc resection
removal of entire tumor and regional lymph node
incisional biopsy
cutting into a tumor and removing a piece to
establish a diagnosis
excisional biopsy
removal of tumor and a margin of normal tissue for
diagnosis and possible cure of small tumors
cryosurgery
freezing a lesion to kill tumor cells
cauterization
burning a lesion to destroy tumor cells
exenteration
wide resection involving removal of tumor, its organ
of origin, and surrounding tissue in the body space
The method of treating cancer using high-energy radiation is
radiation therapy
If tumor tissue requires large doses of radiation to kill cells, it is a/an ______ tumor.
radioresistant
If radiation can cause loss of tumor cells without serious damage to surrounding regions, the tumor is
radiosensitive
A tumor that can be completely eradicated by RT is a/an _____ tumor.
radiocurable
The method of giving radiation in small, repeated doses is:
fractionation
Drugs that increase the sensitivity of tumors to x-rays are:
radiosensitizers