chap 14 Flashcards
The plasticity of skeletal muscle tissue is attributed to 2 dynamic and continuous processes that take place throughout the day. What are they
muscle protein synthesis and muscle protein breakdown
if you only eat protein but don’t exercise what happen with your protein balance
MPS =MPB
if you only exercise without protein intake what happen with your protein balance
MPS <MPB
negative net protein balance
if you exercise and have enough protein what happen with your protein balance
MPS > MPB
positive net protein balance -> muscle hypertrophy
when does the greater MPS (hypertrophy) is induced during resistance training
in the fed state
what is mTOR
mechanistic Target Of Rapamycin
Immunosuppressive and Anti-Tumor properties - reducing protein synthesis as a protective mechanism for cell survival under stress conditions.
what is a Rapamycin
a lipophilic macrolide discovered in 1964 on the island of Rapa Nui (Easter Island)
what is mTORC1 pathway
RE + amino acid + growth factor -> increase mTOR activity -> increase MPS -> hypertrophy
mechanism to activate synthesis during post prandial state (fuel/energy meal)
increase plasma amino acids -> increase MPS
decrease amino acid release from muscle -> decrease MPB
mechanism to activate synthesis during post absorptive state (fuel/energy exercise)
decrease plasma amino acids -> decrease MPS
increase MPB -> increase amino acids release from muscle
what are the place where muscle protein synthesis occurs
In muscle
In plasma
In urine
In saliva
In CO2
explain protein metabolism
- protein intake
- protein break down in amino acids in stomach
- amino acids is absorbed in intestine and sent to liver
- liver extract of AA -> 30% of AA ingest stay in circulation
- AA are transport to muscle via blood
- AA are used for protein synthesis, converted in other AA and are oxidized
The type of proteins consumed will affect:
tissue repair and muscle mass gain
T/F All essential amino acids are necessary for optimal muscle mass gain. Whey protein contains all these amino acids.
T
how munch protein is needed for an endurance athlete and power athlete
1.2-1.4kg for endurance
1.4-1.6 kg for power