CH8 Part 1 Flashcards
Myelin Sheath
Composed of Schwann Cells in PNS, Oligodendrocytes in CNS.
Glial Cells
Schwann Cells
Oligodendrocytes
Astrocytes - guid neural development; synaptic communication regulation; regulate nuerotransmitter levels
Microglia - remove dead cells/debris
Ependymal Cells - Produce and circulate CSF
Nernst Equation
E(ion) = (RT/zF)ln[Xout]/[Xin]
Note that Na Eq potential is +50 mV
K eq is about -90 mV, makes sense as most leak channels are K leak channels meaning the cell tends toward -90 mV
Enzyme that degrades ACh in the neuromuscular junction
Acetylcholinesterase (AChE)
Grey Matter in different locations of nervous system
Nucleus - deep in brain
Cortex - surface of brain
Horn - spinal cord
Ganglion - PNS
Medulla
Or Medulla oblongata
Relays messaging to other parts of brain.
BP, respiratory rythmicity, digestive functions (vomiting)
Pons
Connection between brain stem and cerebellum.
Balance and anti-gravity posture.
Some autonomic functions.
Brainstem
Medulla, pons, midbrain
Midbrain
Relay for visual and auditory info. Contains much of Reticular Activating System (RAS)
Forebrain Components
Diencephalon, telencephalon
Diencephalon
Thalamus - relay and processing system for sensory information.
Hypothalamus - emotion control and autonomic functions; hormone production and risk.
Telencephalon
Forms two cerebral hemispheres (distinct to previous hindbrain and midbrain - one stalk), the cerebrum.
Hemispheres
Cerebrum
Lobes
Frontal Lobe - voluntary movement/complex reasoning
Parietal lobes - general sensations (touch temperature digestion etc.)
Temporal Lobes - auditory and olfactor sensation; short-term memory and language comprehension; emotion
Occipital lobe - visual info
Basal nuclei
Deep in brain.
Voluntary movement and procedural learning habits.
Inhibitory, so works in concert with the cerebellum.
Limbic
Between cerebrum and diencephalon
How many nerves entering CNS?
12 Paired Cranial Nerves
31 pairs of Spinal nerves
Somatic PNS Anatomy
Somatic motor neurons innervate skeletal muslce and use ACH. Cell bodies in brain stem or ventral spinal cord.
All somatic sensory neurons have long dendrite from receptor toward soma which is just outside CNS in a dorsal root ganglion.
Note: Dorsal root ganglia are outside the meninges of the spinal cord and brain.
Autonomic PNS anatomy
Pre-ganglionic neuron: cell body in brain stem or spinal cord. All release ACh.
Post-ganglionic neuron: synapse in ganglion from preganglionic neuron. All parasympathetic release ACh. Most sympathetic release norepinephrine. Synapse on an effector (visceral organs).
Sympathetic efferent pre-ganglionic efferents
All have cell bodies in thoracic or lumbar regions of spinal cord. (Thoracic-lumbar system)
pre-ganglionic axon is quite short. Few ganglia that are large. Post-ganglionic axons are large and project to an effector.
Parasympathetic efferent preganglionic neurons
Cell bodies in brainstem or in sacral portion of spinal cord. (craniosacral system)
preganglionic neurons project long axon to small ganglion located close to effector.
Postganglionic axon is quite short.
Autonomic v. Somatic afferents (sensory)
Autonomic, they can synapse