Ch.5 Intguentary System Flashcards
List the components of the integumentary system
-Skin
-hair
-nails
- sweat glands
- oil glands
Functions of the integumentary system
Protection
Thermoregulation
Cutaneous sensation
Metabolic functions
Blood reservoir
Excretion
Name the two distinct regions of the skin
-epidermis
• superficial
-epithelial
-dermis
•underlies epidermis
-mostly fibrous connective tissue, vascularized
4 cell types make up the epidermis?
•Keratinocytes
•Melanocytes
•Dendritic (Langerhans) cells
•Tactile (Merkel) cells
What type of tissue makes up the epidermis?
Keratinized stratified squamous epithelium, consisting of 4-5 layers of cells each with different characteristics
Keratinocytes
-the most common epidermal cell
-Produce fibrous protein keratin that gives the epidermis its protective properties
-Tightly connected to one another
Melanocytes
-are found in the deepest layers of the epidermis
-Produce pigment melanin
• which is transferred to the keratinocytes and protect the apical surface of those cells from UV damage
Dendritic (Langerhans) cells
-arise from the bone marrow and migrate to the epidermis
-They function as macrophages and are key activators of the immune system
Tactile (Merkel) cells
-Sensory touch receptors; each cell associates with the nerve ending
-Not very abundant
4-5 Layers of the epidermis
From deep to superficial
-stratum basal
-stratum spinosum
-stratum granulosm
-stratum lucidum (only thick skin)
-stratum corneum
Where “ thick skin” located
Thick skin covers area subject to abrasions; palms of the hand, soles of the feet and fingertips
Thin skin
Covers the rest of the body. The stratum lucidum is an absent, and the other layers are thinner.
Stratum basale (base layer)
-deepest epidermal layer from the attached to the dermis
-single roll of stem cells,actively miotic
-occasional tactile cells
-dermal papilla
Stratum spinosum (prickly layer)
-several layers thick
-System of intermediate pre-keratin filaments attached to cell junctions
-Abundant monocytes and dendritic cells
-Langerhan cells which function as macrophage by engulfing bacteria, foreign particles, and damage cells
Stratum granulosum (granular layer)
-4-6 cell deep layer
-cells flatten
-Nuclei and organelles disintegrate
-The cells accumulate two types of granules
•keratohyaline granules, which keep form keratin and upper layers
•lamellar granules who release water resistant glycolipids into the extra cellular space (slows water loss)
-Sales of this layer have thickened plasma membranes to form a waterproof barrier
-All cells above this lay dead. They are too far from capillaries.
Stratum lucidum (clear layer)
-found in only thick skin
-thin translucent band
-2 to 3 rows of flat dead cells, aide in making skin waterproof
• found in Palms, soles of feet and fingertips
Stratum corneum (horny layer)
•20-30 rows of dead flat membraneous sacs
•3/4 epidermal thickness
• Keratin and thicken plasma protects the skin against abrasion
• glycolipids (waterproof) protect from abrasion and penetration barrier against biological chemical, physical assaults