Ch.1 The Microbial World and You Flashcards

1
Q

Microorganisms

A

organisms that are too small to be seen with the unaided eye

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2
Q

Microbes include

A

bacteria, fungi, protozoa, microscopic algae, and viruses

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3
Q

pathogenic

A

disease producing

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4
Q

Microbes can…

A
  • Decompose organic waste
  • Generate oxygen by photosynthesis
  • Produce chemical products such as ethanol, acetone,
    and vitamins
  • Produce fermented foods such as vinegar, cheese,
    and bread
  • Produce products used in manufacturing (e.g.,
    cellulose) and disease treatment (e.g., insulin)
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5
Q

Knowledge of microorganisms allows humans to

A

*prevent food spoilage
* prevent disease
*understand causes and transmission of disease to prevent epidemics

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6
Q

an adult human is composed of __ _______ body cells and harbors another __ _______ bacterial cells

A

30 trillion
40 trillion

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7
Q

a group of microbes that live stably on/in the human body

A

microbiome

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8
Q

the microbiome (3 things)

A

– Help to maintain good health
– Can prevent growth of pathogenic microbes
– May help train the immune system to discriminate
threats

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9
Q

Normal microbiota is the

A

collection of acquired microorganisms on or in a healthy human being

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10
Q

Normal microbiota (3 things)

A

– Begin to be acquired as newborns
– May colonize the body indefinitely
– May colonize the body fleetingly (making them
transient microbiota)

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11
Q

colonization can only occur at body sites that ______ _______ and the right environment for the ________ __ _______

A

provide nutrients
microbes to flourish

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12
Q

The Human Microbiome Project

A

– Begun in 2007
– Goal of determining the makeup of typical microbiota of
various areas of the body
– Secondary goal of understanding relationship between
changes in microbiome and human diseases

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13
Q

The National Microbiome Initiative (NMI)

A

– Begun in 2016
– Explores the role microbes play in different ecosystems

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14
Q

Who established the system of scientific nomenclature in 1735

A

Carolus Linnaeus

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15
Q

Each organism has two names

A

The genus and the specific epithet

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16
Q

Scientific names

A

– Are italicized or underlined
▪ The genus is capitalized; the specific epithet is
lowercase
– Are “Latinized” and used worldwide
– May be descriptive or honor a scientist

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17
Q

After the first use, scientific names may be
abbreviated with the first letter of the genus and the
specific epithet:

A

– Escherichia coli and Staphylococcus aureus
are found in the human body
– E. coli is found in the large intestine, and S.
aureus is on skin

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18
Q

Types of Microorganisms

A
  • Bacteria
  • Archaea
  • Fungi
  • Protozoa
  • Algae
  • Viruses
  • Multicellular Animal Parasites
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19
Q

Bacteria

A
  • Prokaryotes
    – “Prenucleus”
  • Single-celled
  • Peptidoglycan cell walls
  • Divide via binary fission
  • Derive nutrition from organic or inorganic chemicals or
    photosynthesis
  • May “swim” by using moving appendages called flagella
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20
Q

Archaea

A
  • Are prokaryotes
  • Lack peptidoglycan cell walls
    – May lack cell wall entirely
  • Often live in extreme environments
  • Include:
    – Methanogens
    – Extreme halophiles
    – Extreme thermophiles
  • Generally not known to cause disease in humans
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21
Q

Fungi

A
  • Eukaryotes
    – Distinct nucleus surrounding DNA genetic material
  • Chitin cell walls
  • Absorb organic chemicals for energy
  • Yeasts are unicellular
  • Molds and mushrooms are multicellular
    – Molds consist of masses of mycelia, which are
    composed of filaments called hyphae
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22
Q

Protozoa

A
  • Eukaryotes
  • Absorb or ingest organic chemicals
  • May be motile via pseudopods, cilia, or flagella
  • Free-living or parasitic (derive nutrients from a living
    host)
    – Some are photosynthetic
  • Reproduce sexually or asexually
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23
Q

Algae

A
  • Eukaryotes
  • Cellulose cell walls
  • Found in freshwater, saltwater, and soil
  • Use photosynthesis for energy
    – Produces oxygen and carbohydrates
  • Sexual and asexual reproduction possible
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24
Q

Viruses

A
  • Acellular
  • Consist of DNA or RNA core
  • Core is surrounded by a protein coat
    – Coat may be enclosed in a lipid envelope
  • Are replicated only when they are in a living host cell
    – Inert outside living hosts
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25
Multicellular Animal Parasites
* Eukaryotes * Multicellular animals * Not strictly microorganisms * Parasitic flatworms and roundworms are called helminths – Some microscopic stages in their life cycles
26
Classification of Microorganisms
developed by Carl Woese in 1978
27
Three domains based on cellular organization
– Bacteria – Archaea – Eukarya ▪ Protists ▪ Fungi ▪ Plants ▪ Animals
28
1665: Robert Hooke reported that all living things are composed of little boxes, or "cells"
- Marked the beginning of cell theory: all living things are composed of cells - Perspective: Thomas Edison light bulb 1879
29
Anton van Leeuwenhoek observed the first microbes from
1623 to 1673
30
Magnifying lenses were used to view
Animalcules
31
Spontaneous generation
the hypothesis that life arises from nonliving matter; a "vital force" is necessary for life
32
Biogenesis
the hypothesis that living cells arise only from preexisting living cells
33
1858: Rudolf Virchow
said cells arise from preexisting cells
34
Pasteur also used S-shaped flasks
keep microbes out but let air in
35
Pasteur showed that microbes were responsible for
fermentation
36
fermentation
the microbial conversion of sugar to alcohol in the absence of air
37
Pasteurization
the application of a high heat for a short time to kill harmful bacteria in beverages
38
Vaccination 1796
Edward Jenner
39
Immunity
protection from disease
40
Chemotherapy
treatment of disease with chemicals
41
Antibiotics
chemicals produced by bacteria and fungo that inhibit or kill other microbes
42
Chemotherapeutic agents used to treat infectious disease can be
synthetic drugs or antibiotics
43
1928: Alexander Fleming
discovered the first antibiotic
44
Penicillium fungus made...
penicillin that killed S. aureus
45
overuse can lead to
resistance
46
Bacteriology
study of bacteria
47
Mycology
study of fungi
48
Parasitology
study of protozoa and parasitic worms
49
Immunology
study of immunity
50
Virology
study of viruses
51
Microbial genetics
study of how microbes inherit traits
52
Molecular biology
study of how DNA directs protein synthesis
53
Genomics
study of an organisms genes; has provided new tools for classifying microorganisms
54
Recombinant DNA
DNA made from two different sources
55
Microbial ecology
study of the relationship between microorganisms and their environment
56
Biotechnology
the use of microbes for practical applications, such as producing foods and chemicals
57
Recombinant DNA technology
enables bacteria and fungi to produce a variety of proteins, vaccines, and enzymes
58
Normal microbiota
microbes normally present in and on the human body
59
Resistance
the ability of the body to ward off disease
60
Emerging infectious diseases (EIDs)
new diseases and diseases increasing in incidence
61
Zika virus disease
– Virus discovered in 1947 in Uganda – Human epidemics in Micronesia 2007, then in French Polynesia and Brazil in 2013–2015 – Spread by bite of an infected Aedes mosquito; also transmitted by sexual contact – Infection during pregnancy can result in severe birth defects
62
Middle Easy respiratory syndrome (MERS)
– Caused by Middle East respiratory syndrome coronavirus (MERS-CoV) – Common to SARS ▪ Severe acute respiratory syndrome – 1,800 confirmed human cases and 630 deaths since 2014
63
H1N1 influenza
– Also known as swine flu – First detected in the United States in 2009 ▪ Declared a pandemic, or worldwide large-scale outbreak, by WHO in 2009
64
Avian influenza A (H5N1)
– Influenza A virus – Primarily in waterfowl and poultry – Sustained human-to-human transmission has not yet occurred
65
Methicillin-resistant Staphylococcus aureus (MRSA)
-- 1950s: Penicillin resistance developed – 1980s: Methicillin resistance – 1990s: MRSA resistance to vancomycin reported ▪ VISA: vancomycin-intermediate S. aureus ▪ VRSA: vancomycin-resistant S. aureus
66
Ebola hemorrhagic fever (EHF)
– Ebola virus – Causes fever, hemorrhaging, and blood clotting – Transmitted via contact with infected blood or body fluids – First identified near Ebola River, Congo – 2014 outbreak in Guinea; over 28,000 infected over 2 years, with 1/3 of those infected dead
67
Marburg virus
– Causes hemorrhagic fever similar to Ebola – First cases in laboratory workers in Europe who handled African green monkeys from Uganda – 13 outbreaks identified in Africa between 1975 and 2016 ▪ Involving 1 to 252 people, with 57% mortality – African fruit bats are the natural reservoir for the virus (and also suspected of being the reservoir for Ebola virus)