Ch 9 Asthma Flashcards

1
Q

Is asthma reversible?

A

Yes but not necessarily curable

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2
Q

Symptoms of asthma attack

A

Shortness of breath
Coughing
Wheezing
Tightness in the chest
In the extreme, person can not breath

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3
Q

What can trigger an asthma attack?

A

Cold/heat
Humidity
Exercise
Smoking
Allergens (ex: pollen)
Atopic/non-atopic
Viral infections
NSAIDs
Food additives
Psychomatic factors

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4
Q

Pathophysiology of asthma (3)

A

Inflamed tissue/red/swollen/edema/excessive mucous production
Bronchial hyper responsiveness to other types of stimuli
Immune cells enter the lung tissues in some cases

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5
Q

what composante causes the inflammation and brochoconstriction?

A

Leukotrienes

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6
Q

The underlying inflammation is thought to be ____

A

chronic, so a person will always have some level of inflammation in their lungs

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7
Q

two major goals of a drug for asthma

A

treat asthma attack symptoms
treat the underlying chronic inflammation

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8
Q

4 types of asthma

A

Intermittent
Mild persistent
Moderate persistent
Severe persistent

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9
Q

Intermittent asthma

A

1-2 attacks per week, waking up 1 time per month

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10
Q

Mild persistent asthma

A

3-6 attacks per week, waking up 2-3 times per month

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11
Q

Moderate persistent asthma

A

7 attacks per week, waking up 4 times per month

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12
Q

Severe persistent asthma

A

8 or more attacks per week, waking up 5 or more times per month

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13
Q

What happens to the force expiratory volume during severe persistent asthma?

A

It is between 60% and 80% in the severe form

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14
Q

What is forced expiratory volume?

A

A test where they try to expel as much as possible. The lower the value, the worse is the lung function

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15
Q

What are short acting beta-agonist (SABA)?

A

quick relief
prevent an imminent attack
not taken routinely, only as needed
prevent brochonconstriction

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16
Q

What are anticholinergics?

A

similar in use to short acting drugs
many side effects so not commonly used
prevent brochoconstriction

17
Q

What are corticosteroids (oral)?

A

use when needed for quick relief
many side effects
prevent brochoconstriction

18
Q

What are long acting beta-agonist (LABA)?

A

inhaled
prevent bronchoconstriction
are slower than SABA
should not be used as needed
use regularly

19
Q

What are corticosteroids (inhaled)?

A

do not affect bronchoconstriction/dilation
reduces inflammatory reactions in tissue
used regularly
increases the response of SABA

20
Q

2 other examples of drugs used rarely

A

Mast cell stabilizing drugs
Leukotriene modifiers

21
Q

What is the issue with mast cell stabilizing drugs or leukotriene modifiers?

A

Issues with effectiveness and toxicity, they have lower TI than the other drugs

22
Q

Do you rinse your mouth after using the inhaler?

A

Only needed if taking corticosteroids

23
Q
A